用于微流控分析设备的数字光处理3D打印技术的最新进展。

Recent developments in digital light processing 3D-printing techniques for microfluidic analytical devices.

作者信息

Amini Ali, Guijt Rosanne M, Themelis Thomas, De Vos Jelle, Eeltink Sebastiaan

机构信息

Department of Chemical Engineering, Vrije Universiteit Brussel (VUB), Pleinlaan 2, Brussels B-1050, Belgium.

Centre for Regional and Rural Futures, Deakin University, Geelong, Australia.

出版信息

J Chromatogr A. 2023 Mar 15;1692:463842. doi: 10.1016/j.chroma.2023.463842. Epub 2023 Feb 1.

DOI:10.1016/j.chroma.2023.463842

PMID:36745962

Abstract

Digital light processing (DLP) 3D printing is rapidly advancing and has emerged as a powerful additive manufacturing approach to fabricate analytical microdevices. DLP 3D-printing utilizes a digital micromirror device to direct the projected light and photopolymerize a liquid resin, in a layer-by-layer approach. Advances in vat and lift design, projector technology, and resin composition, allow accurate fabrication of microchannel structures as small as 18 × 20 µm. This review describes the latest advances in DLP 3D-printing technology with respect to instrument set-up and resin formulation and highlights key efforts to fabricate microdevices targeting emerging (bio-)analytical chemistry applications, including colorimetric assays, extraction, and separation.

摘要

数字光处理（DLP）3D打印技术正在迅速发展，并已成为一种强大的增材制造方法，用于制造分析微器件。DLP 3D打印利用数字微镜器件来引导投射光，并以逐层方式使液体树脂光聚合。在光固化槽和升降设计、投影仪技术以及树脂成分方面的进展，使得能够精确制造小至18×20微米的微通道结构。本文综述了DLP 3D打印技术在仪器设置和树脂配方方面的最新进展，并重点介绍了针对新兴（生物）分析化学应用制造微器件的关键成果，包括比色测定、萃取和分离。