Research and Innovation, Greater Manchester Mental Health NHS Foundation Trust, Manchester, UK
School of Psychological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.
BMJ Open. 2023 Feb 6;13(2):e067342. doi: 10.1136/bmjopen-2022-067342.
Cardiovascular disease is among the most common of non-communicable diseases, affecting 13.9 million children and young people (CYP) globally. Survival rates for CYP with heart conditions are rising, however, support for adjusting to life with a heart condition is lacking, as such it is unsurprising that one in three suffer from anxiety, depression or adjustment disorder. The proposed review aims to identify and assess the effectiveness of physical and mental health interventions across physical and mental health outcomes in young people with cardiac conditions using narrative synthesis and meta-analysis if appropriate.
Embase, Medline, PubMed, PsycINFO, Cochrane Databases, Web of Science and reference lists of relevant publications will be searched from 1980 to June 2022 for articles published in English or Italian. Screening, data extraction, intervention coding and risk of bias will be performed by two independent reviewers using an extraction checklist. Intervention content and features will be identified and reported using the Template for Intervention Description and Replication checklist. A narrative review of the included studies will be conducted. If possible and appropriate, a random-effects model meta-analysis will be conducted to calculate the pooled within-group and between-group effect sizes for the primary outcome measures. If sufficient data are available, a subgroup meta-analysis will investigate whether specific intervention types are associated with different levels of intervention effectiveness.
This systematic review does not directly involve the use of human beings, therefore, there is no requirement for ethical approval. Findings will be disseminated through peer-reviewed publication and in various media, such as conferences, congresses or symposia.
CRD42022330582.
心血管疾病是最常见的非传染性疾病之一，影响着全球 1390 万儿童和青少年（CYP）。患有心脏疾病的 CYP 的生存率正在上升，但缺乏适应心脏疾病的生活的支持，因此，三分之一的人患有焦虑、抑郁或适应障碍并不奇怪。拟议的综述旨在通过叙述性综合和荟萃分析（如果合适的话），确定和评估针对患有心脏疾病的年轻人的身心健康干预措施在身心健康结果方面的有效性。
从 1980 年到 2022 年 6 月，将在英文或意大利文发表的文章中，从 Embase、Medline、PubMed、PsycINFO、Cochrane 数据库、Web of Science 和相关出版物的参考文献中搜索。使用提取清单，由两名独立审查员进行筛选、数据提取、干预编码和偏倚风险评估。将使用干预描述和复制清单（Template for Intervention Description and Replication checklist）识别和报告干预内容和特征。将对纳入的研究进行叙述性综述。如果可能且合适，将进行随机效应模型荟萃分析，以计算主要结局指标的组内和组间效应大小的合并值。如果有足够的数据，将进行亚组荟萃分析，以调查特定的干预类型是否与不同水平的干预效果相关。
这项系统综述不直接涉及人类的使用，因此不需要伦理批准。研究结果将通过同行评审出版物和各种媒体（如会议、大会或研讨会）进行传播。
PROSPERO 注册号：CRD42022330582。
