Department of Psychology and Logopedics, University of Helsinki, Helsinki, Finland
Finnish Institute for Health and Welfare, Helsinki, Finland.
J Epidemiol Community Health. 2023 May;77(5):298-304. doi: 10.1136/jech-2022-219674. Epub 2023 Feb 6.
A study was undertaken to examine the association between multiple indicators of socioeconomic position (SEP) at the age of 30 and the subsequent risk of the most common mental disorders.
All persons born in Finland between 1966 and 1986 who were alive and living in Finland at the end of the year when they turned 30 were included. Educational attainment, employment status and personal total income were used as the alternative measures of SEP. Cox proportional hazards models were used to examine the association of SEP at the age of 30 with later risk of mental disorders. Additional analyses were conducted using a sibling design to account for otherwise unobserved shared family characteristics. Competing risks models were used to estimate absolute risks.
The study population included 1 268 768 persons, 26% of whom were later diagnosed with a mental disorder. Lower SEP at age 30 was consistently associated with a higher risk of being later diagnosed with a mental disorder, even after accounting for shared family characteristics and prior history of a mental disorder. Diagnosis-specific analyses showed that the associations were considerably stronger when substance misuse or schizophrenia spectrum disorders were used as an outcome. Absolute risk analyses showed that, by the age of 52 years, 58% of persons who had low educational attainment at the age of 30 were later diagnosed with a mental disorder.
Poor SEP at the age of 30 is associated with an increased risk of being later diagnosed with a mental disorder.
本研究旨在探讨 30 岁时多种社会经济地位(SEP)指标与随后最常见精神障碍风险之间的关系。
所有在芬兰出生于 1966 年至 1986 年之间、在 30 岁结束时仍然在世且居住在芬兰的人都被纳入本研究。教育程度、就业状况和个人总收入被用作 SEP 的替代衡量指标。使用 Cox 比例风险模型来研究 30 岁时的 SEP 与以后发生精神障碍的风险之间的关联。使用同胞设计进行额外分析,以解释其他未观察到的共同家庭特征。使用竞争风险模型来估计绝对风险。
本研究人群包括 1268768 人,其中 26%的人后来被诊断出患有精神障碍。30 岁时较低的 SEP 与以后被诊断出患有精神障碍的风险增加始终相关,即使考虑到共同家庭特征和以前的精神障碍史也是如此。特定于诊断的分析表明,当将物质滥用或精神分裂症谱系障碍作为结局时,关联更为显著。绝对风险分析表明,到 52 岁时,30 岁时教育程度较低的人中,有 58%后来被诊断出患有精神障碍。
30 岁时较差的 SEP 与以后被诊断出患有精神障碍的风险增加相关。