Guo Yi-Qiang, Ju Qing-Mei, You Miaoning, Liu Yang, Yusuf Azlina, Soon Lean Keng
School of Nursing, Capital Medical University, Beijing, China.
Emergency General Hospital, Beijing, China.
BMC Nurs. 2023 Feb 6;22(1):33. doi: 10.1186/s12912-023-01184-1.
This study aimed to assess the level of depression, anxiety and stress among metastatic breast cancer (MBC) patients undergoing chemotherapy (CT) in Beijing, China.
A cross-sectional study was conducted on 176 MBC women receiving CT, selected by purposive sampling. Data were collected using self-administered questionnaires that included participants' socio-demographic status, DASS-21 and Brief COPE. Data were analyzed using descriptive statistics and general linear regression analysis.
The incidence of depression, anxiety and stress among MBC women were 52.3%, 60.2% and 36.9%, respectively. General linear regression showed that age, marital status, monthly income, physical functioning, emotional functioning, pain, dyspnea, and appetite loss were associated with depression. All variance determined the depression (R) was 35.6%. Marital status, self-blame and behavioral disengagement were the predictors of stress and accounted for a 35.4% stress variance in MBC women.
Our study demonstrated depression, anxiety, and stress prevalence are high in MBC women. Assessment of psychological distress (depression, anxiety, and stress) is important to recognise MBC patients who need help and further medical and mental help support. This study's findings can increasingly highlight that depression, anxiety, and stress are substantial problems in MBC patients. Therefore, psychological interventions are needed to reduce depression, anxiety, and stress for MBC patients.
本研究旨在评估中国北京接受化疗（CT）的转移性乳腺癌（MBC）患者的抑郁、焦虑和压力水平。
采用目的抽样法对176名接受CT的MBC女性进行横断面研究。使用包括参与者社会人口学状况、抑郁焦虑压力量表-21（DASS-21）和简易应对方式问卷（Brief COPE）的自填式问卷收集数据。采用描述性统计和一般线性回归分析进行数据分析。
MBC女性中抑郁、焦虑和压力的发生率分别为52.3%、60.2%和36.9%。一般线性回归显示，年龄、婚姻状况、月收入、身体功能、情绪功能、疼痛、呼吸困难和食欲减退与抑郁有关。所有确定抑郁的方差（R）为35.6%。婚姻状况、自责和行为脱离是压力的预测因素，在MBC女性中占压力方差的35.4%。
我们的研究表明，MBC女性中抑郁、焦虑和压力的患病率很高。评估心理困扰（抑郁、焦虑和压力）对于识别需要帮助以及进一步医疗和心理帮助支持的MBC患者很重要。本研究结果越来越突出表明，抑郁、焦虑和压力是MBC患者的重大问题。因此，需要采取心理干预措施来减轻MBC患者的抑郁、焦虑和压力。
