• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

结合分析流行病学和基因组监测，鉴定与血清型 Heidelberg 亚种中抗生素耐药性传播相关的危险因素。

Combining analytical epidemiology and genomic surveillance to identify risk factors associated with the spread of antimicrobial resistance in subsp. serovar Heidelberg.

机构信息

Department of Population Medicine, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada.

National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada.

出版信息

Microb Genom. 2022 Nov;8(11). doi: 10.1099/mgen.0.000891.

DOI:10.1099/mgen.0.000891
PMID:36748560
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9836098/
Abstract

Antimicrobial resistance (AMR) has become a critical threat to public health worldwide. The use of antimicrobials in food and livestock agriculture, including the production of poultry, is thought to contribute to the dissemination of antibiotic resistant bacteria (ARB) and the genes and plasmids that confer the resistant phenotype (ARG). However, the relative contribution of each of these processes to the emergence of resistant pathogens in poultry production and their potential role in the transmission of resistant pathogens in human infections, requires a deeper understanding of the dynamics of ARB and ARG in food production and the factors involved in the increased risk of transmission.

摘要

抗菌药物耐药性（AMR）已成为全球公共卫生的一个重大威胁。人们认为，包括家禽生产在内的食品和家畜农业中抗菌药物的使用，助长了抗药性细菌（ARB）以及赋予耐药表型的基因和质粒（ARG）的传播。然而，这些过程中每一个过程对抗药性病原体在家禽生产中的出现的相对贡献，及其在人类感染中抗药性病原体传播的潜在作用，都需要深入了解食品生产中 ARB 和 ARG 的动态以及增加传播风险的相关因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/780b/9836098/c4a59824d1ba/mgen-8-891-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/780b/9836098/27121fc56991/mgen-8-891-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/780b/9836098/0a1570c8ef16/mgen-8-891-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/780b/9836098/d9ad481d5243/mgen-8-891-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/780b/9836098/bb4496e0b810/mgen-8-891-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/780b/9836098/9f3f733ae3cb/mgen-8-891-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/780b/9836098/c4a59824d1ba/mgen-8-891-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/780b/9836098/27121fc56991/mgen-8-891-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/780b/9836098/0a1570c8ef16/mgen-8-891-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/780b/9836098/d9ad481d5243/mgen-8-891-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/780b/9836098/bb4496e0b810/mgen-8-891-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/780b/9836098/9f3f733ae3cb/mgen-8-891-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/780b/9836098/c4a59824d1ba/mgen-8-891-g006.jpg

相似文献

1
Combining analytical epidemiology and genomic surveillance to identify risk factors associated with the spread of antimicrobial resistance in subsp. serovar Heidelberg.结合分析流行病学和基因组监测，鉴定与血清型 Heidelberg 亚种中抗生素耐药性传播相关的危险因素。
Microb Genom. 2022 Nov;8(11). doi: 10.1099/mgen.0.000891.
2
Dynamics of Antimicrobial Resistance and Genomic Epidemiology of Multidrug-Resistant Salmonella enterica Serovar Indiana ST17 from 2006 to 2017 in China.2006 年至 2017 年中国耐多药肠炎沙门氏菌血清型印第安纳 ST17 的耐药性动态和基因组流行病学研究。
mSystems. 2022 Aug 30;7(4):e0025322. doi: 10.1128/msystems.00253-22. Epub 2022 Jul 21.
3
Draft genome sequences of two ciprofloxacin-resistant Salmonella enterica subsp. enterica serotype Kentucky ST198 isolated from retail chicken carcasses in Egypt.两株从埃及零售鸡肉中分离的耐环丙沙星肠炎沙门氏菌血清型肯塔基 ST198 的基因组草图序列。
J Glob Antimicrob Resist. 2018 Sep;14:101-103. doi: 10.1016/j.jgar.2018.06.012. Epub 2018 Jun 30.
4
Salmonella Yoruba: A rare serotype revealed through genomic sequencing along the farm-to-fork continuum of an intensive poultry farm in KwaZulu-Natal, South Africa.约鲁巴沙门氏菌：通过对南非夸祖鲁-纳塔尔省一个密集型家禽养殖场从农场到餐桌连续体的基因组测序发现的一种罕见血清型。
Acta Trop. 2022 Oct;234:106620. doi: 10.1016/j.actatropica.2022.106620. Epub 2022 Jul 27.
5
Whole-Genome Sequence Analysis of an Extensively Drug-Resistant Salmonella enterica Serovar Agona Isolate from an Australian Silver Gull () Reveals the Acquisition of Multidrug Resistance Plasmids.对从澳大利亚银鸥中分离出的一株广泛耐药的肠炎沙门氏菌血清型阿贡纳进行全基因组序列分析，揭示了其获得了多药耐药质粒。
mSphere. 2020 Nov 25;5(6):e00743-20. doi: 10.1128/mSphere.00743-20.
6
Genomic characterization of multidrug-resistant Salmonella Heidelberg E2 strain isolated from chicken carcass in southern Brazil.巴西南部鸡肉中分离的耐多药肠炎沙门氏菌 E2 株的基因组特征
Int J Food Microbiol. 2022 Oct 16;379:109863. doi: 10.1016/j.ijfoodmicro.2022.109863. Epub 2022 Jul 30.
7
Global phylogenomics of multidrug-resistant Salmonella enterica serotype Kentucky ST198.全球耐多药沙门氏菌肠炎亚种肯塔基 ST198 的系统发生基因组学研究
Microb Genom. 2019 Jul;5(7). doi: 10.1099/mgen.0.000269. Epub 2019 May 20.
8
Draft genome sequences of 25 Salmonella enterica serovar Agona strains isolated from poultry and associated food products harbouring multiple antibiotic resistance genes.25 株从禽肉及相关食品中分离的肠炎沙门氏菌血清型 Agona 菌株的基因组草图序列，这些菌株携带多种抗生素耐药基因。
J Glob Antimicrob Resist. 2022 Jun;29:131-135. doi: 10.1016/j.jgar.2022.02.013. Epub 2022 Feb 25.
9
Genomic diversity and resistome profiles of Salmonella enterica subsp. enterica serovar Kentucky isolated from food and animal sources in Ireland.从爱尔兰食物和动物源中分离的肠炎沙门氏菌亚种肯塔基血清型的基因组多样性和耐药组特征。
Zoonoses Public Health. 2022 Feb;69(1):1-12. doi: 10.1111/zph.12884. Epub 2021 Oct 30.
10
Horizontal Gene Transfer and Acquired Antibiotic Resistance in Salmonella enterica Serovar Heidelberg following Incubation in Broiler Ceca.在肉鸡盲肠中孵育后，肠炎沙门氏菌 Heidelberg 血清型的水平基因转移和获得性抗生素耐药性。
Appl Environ Microbiol. 2019 Oct 30;85(22). doi: 10.1128/AEM.01903-19. Print 2019 Nov 15.

引用本文的文献

1
Addressing the global challenge of bacterial drug resistance: insights, strategies, and future directions.应对细菌耐药性的全球挑战：见解、策略与未来方向。
Front Microbiol. 2025 Feb 24;16:1517772. doi: 10.3389/fmicb.2025.1517772. eCollection 2025.
2
Analysis of Antimicrobial Resistance in Bacterial Pathogens Recovered from Food and Human Sources: Insights from 639,087 Bacterial Whole-Genome Sequences in the NCBI Pathogen Detection Database.从食品和人类来源分离的细菌病原体的抗菌药物耐药性分析：来自NCBI病原体检测数据库中639,087个细菌全基因组序列的见解
Microorganisms. 2024 Mar 30;12(4):709. doi: 10.3390/microorganisms12040709.
3

本文引用的文献

1
Reduction in Antimicrobial Use and Resistance to Salmonella, Campylobacter, and Escherichia coli in Broiler Chickens, Canada, 2013-2019.2013-2019 年加拿大肉鸡中沙门氏菌、弯曲杆菌和大肠杆菌的抗菌药物使用减少和耐药性降低
Emerg Infect Dis. 2021 Sep;27(9):2434-2444. doi: 10.3201/eid2709.204395.
2
Molecular characterization of Campylobacter spp. recovered from beef, chicken, lamb and pork products at retail in Australia.从澳大利亚零售的牛肉、鸡肉、羊肉和猪肉产品中回收的弯曲杆菌属的分子特征。
PLoS One. 2020 Jul 30;15(7):e0236889. doi: 10.1371/journal.pone.0236889. eCollection 2020.
3
Emergence of a Novel Salmonella enterica Serotype Reading Clonal Group Is Linked to Its Expansion in Commercial Turkey Production, Resulting in Unanticipated Human Illness in North America.
-positive serovars Agona and Derby are prevalent among food-producing animals in Chongqing, China.
在中国重庆，产肉食品动物中血清型阿贡纳和德比呈阳性的情况很普遍。
Front Microbiol. 2023 May 25;14:1011719. doi: 10.3389/fmicb.2023.1011719. eCollection 2023.
新型肠炎沙门氏菌血清型阅读克隆群的出现与其在商业火鸡生产中的扩张有关，导致北美的人类疾病意料之外。
mSphere. 2020 Apr 15;5(2):e00056-20. doi: 10.1128/mSphere.00056-20.
4
Evaluation of whole-genome sequencing for outbreak detection of Verotoxigenic Escherichia coli O157:H7 from the Canadian perspective.从加拿大视角评估全基因组测序用于产志贺毒素大肠杆菌O157:H7疫情检测的情况。
BMC Genomics. 2018 Dec 4;19(1):870. doi: 10.1186/s12864-018-5243-3.
5
Hotspot mutations and ColE1 plasmids contribute to the fitness of Salmonella Heidelberg in poultry litter.热点突变和 ColE1 质粒有助于海德堡沙门氏菌在禽粪中的适应性。
PLoS One. 2018 Aug 31;13(8):e0202286. doi: 10.1371/journal.pone.0202286. eCollection 2018.
6
MOB-suite: software tools for clustering, reconstruction and typing of plasmids from draft assemblies.MOB-suite：用于从草图组装中对质粒进行聚类、重建和分型的软件工具。
Microb Genom. 2018 Aug;4(8). doi: 10.1099/mgen.0.000206. Epub 2018 Jul 27.
7
GrapeTree: visualization of core genomic relationships among 100,000 bacterial pathogens.葡萄树：可视化 100000 种细菌病原体核心基因组关系。
Genome Res. 2018 Sep;28(9):1395-1404. doi: 10.1101/gr.232397.117. Epub 2018 Jul 26.
8
Agriculture and Agri-Food Canada's research program on antimicrobial resistance.加拿大农业和农业食品部关于抗菌药物耐药性的研究项目。
Can Commun Dis Rep. 2017 Nov 2;43(11):224-227. doi: 10.14745/ccdr.v43i11a03.
9
A genomic overview of the population structure of Salmonella.沙门氏菌群体结构的基因组概述。
PLoS Genet. 2018 Apr 5;14(4):e1007261. doi: 10.1371/journal.pgen.1007261. eCollection 2018 Apr.
10
Comparative analysis of core genome MLST and SNP typing within a European Salmonella serovar Enteritidis outbreak.对欧洲肠炎沙门氏菌暴发的核心基因组 MLST 和 SNP 分型的比较分析。
Int J Food Microbiol. 2018 Jun 2;274:1-11. doi: 10.1016/j.ijfoodmicro.2018.02.023. Epub 2018 Feb 28.