Programa de Pós-graduação em Ciências Médicas: Endocrinologia, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brasil.
Divisão de Endocrinologia, Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, RS, Brasil.
Arch Endocrinol Metab. 2023 Mar 30;67(3):385-394. doi: 10.20945/2359-3997000000596. Epub 2023 Feb 7.
The objective of this study was to verify the impact of carbohydrate counting (CC) on glycemic control and body weight variation (primary and secondary outcomes, respectively) between consultations in patients with diabetes mellitus (T1D) followed at a tertiary hospital in southern Brazil in a public health system environment. We also sought to investigate CC adherence.
This retrospective cohort study included 232 patients with T1D who underwent nutritional monitoring at a referral hospital for diabetes care between 2014 and 2018. To assess primary and secondary outcomes, data from 229 patients, 49 of whom underwent CC during this period and 180 individuals who used fixed doses of insulin, were analyzed. The impact of CC on glycemic control was assessed with the mean glycated hemoglobin (HbA1c) level at all consultations during the follow-up period.
In the model adjusted for the most confounders (except pregnancy), the mean HbA1c was better in the CC group (8.66 ± 0.4% vs. 9.36 ± 0.39%; p = 0.016), and body weight variation was lower (0.13 ± 0.28 kg vs. 0.53 ± 0.24 kg; p = 0.024). Adherence to CC was reported in 69.2% of consultations.
CC optimized the glycemic control of individuals with T1D, resulting in less weight variation than in the fixed insulin dose group, which indicates that CC is an important care strategy for these patients.
本研究旨在验证在巴西南部一家公立医院的三级医院接受治疗的糖尿病患者(T1D)中,通过计算碳水化合物(CC)对血糖控制(主要结果)和体重变化(次要结果)的影响,分别在两次就诊之间。我们还试图调查 CC 的依从性。
这项回顾性队列研究包括了 232 名在 2014 年至 2018 年期间在一家糖尿病治疗转诊医院接受营养监测的 T1D 患者。为了评估主要和次要结果,对 229 名患者的数据进行了分析,其中 49 名患者在此期间接受了 CC,180 名患者使用了固定剂量的胰岛素。通过评估整个随访期间所有就诊时的平均糖化血红蛋白(HbA1c)水平来评估 CC 对血糖控制的影响。
在调整了大多数混杂因素(除了妊娠)的模型中,CC 组的平均 HbA1c 水平更好(8.66±0.4%比 9.36±0.39%;p=0.016),体重变化更低(0.13±0.28kg 比 0.53±0.24kg;p=0.024)。报告了 69.2%的就诊时 CC 的依从性。
CC 优化了 T1D 患者的血糖控制,导致体重变化低于固定胰岛素剂量组,这表明 CC 是这些患者的重要治疗策略。