Dimopoulou Maria, Bargiota Alexandra, Barmpa Eleftheria, Outskouni Zozo, Stagos Dimitrios, Trachana Varvara, Androutsos Odysseas, Gortzi Olga
Department of Agriculture Crop Production and Rural Environment, School of Agriculture Sciences, University of Thessaly, 38446 Volos, Greece.
Department of Endocrinology and Metabolic Diseases, Faculty of Medicine, School of Health Sciences, University Hospital of Larissa, University of Thessaly, 41334 Larissa, Greece.
Foods. 2024 Dec 20;13(24):4123. doi: 10.3390/foods13244123.
Daily, more and more people consume snack bars that may have an impact on blood glucose levels. The aim of the present study was to compare the acute effects of a common snack and a plant-based snack bar (PB) that was developed at the University of Thessaly as a functional diabetic snack on blood glucose and insulin in patients with type 2 diabetes mellitus (T2DM). Adults with T2DM ( = 10) treated with oral medications were studied in a randomized, crossover clinical trial. On each trial day, postprandial glucose and insulin levels were measured at 30, 60, 90, and 120 min, and a morning snack containing 25 g of carbohydrate was consumed. The procedure was carried out on 2 days, with one of the test meals being consumed on each day. Consumption of a PB snack bar resulted in a smaller and steeper increase in postprandial glucose and insulin levels compared with the usual snack, and there were significant differences 60 and 90 min after consumption of the two tested snacks. The PB snack bar is rich in protein, fiber, vitamins, and minerals and can therefore be suggested as a nutritious and convenient snack for patients with T2DM. In addition, the extract of the snack bar was tested for its bioactivity in human cell cultures.
每天，越来越多的人食用可能会对血糖水平产生影响的能量棒。本研究的目的是比较一种常见能量棒和一种由色萨利大学研发的作为功能性糖尿病患者零食的植物基能量棒（PB）对2型糖尿病（T2DM）患者血糖和胰岛素的急性影响。在一项随机交叉临床试验中，对10名接受口服药物治疗的T2DM成年患者进行了研究。在每个试验日，分别在30、60、90和120分钟测量餐后血糖和胰岛素水平，并食用一份含有25克碳水化合物的上午零食。该过程在两天内进行，每天食用其中一种测试餐。与普通能量棒相比，食用PB能量棒后餐后血糖和胰岛素水平的升高幅度更小且更陡峭，在食用两种测试能量棒60和90分钟后存在显著差异。PB能量棒富含蛋白质、纤维、维生素和矿物质，因此可作为T2DM患者营养丰富且方便的零食。此外，还对该能量棒的提取物在人类细胞培养中的生物活性进行了测试。
