Tanaka S, Suzuki T, Numata T
Br J Vener Dis. 1978 Dec;54(6):369-73. doi: 10.1136/sti.54.6.369.
Clinical investigations using the Treponema pallidum immune adherence (TPIA) test as reported by Nelson (1953) were performed only by Olansky et al in 1954. In this paper an improved method of the TPIA test is described. The test was simple to perform and was highly specific for antitreponemal antibody. Furthermore, as it was possible to use heated T. pallidum as antigen the antigen suspension could be preserved for long periods. The TPIA test for syphilis was evaluated by examining the sera from 40 healthy subjects and from 166 patients with syphilis.
正如纳尔逊(1953年)所报道的,使用梅毒螺旋体免疫黏附(TPIA)试验进行的临床研究在1954年只有奥兰斯基等人开展过。本文描述了一种改良的TPIA试验方法。该试验操作简单,对抗梅毒抗体具有高度特异性。此外,由于可以使用加热后的梅毒螺旋体作为抗原,抗原悬液能够长期保存。通过检测40名健康受试者和166名梅毒患者的血清对梅毒TPIA试验进行了评估。