Grigoriev A I, Popova I A, Ushakov A S
Institute of Biomedical Problems, Moscow, U.S.S.R.
Aviat Space Environ Med. 1987 Sep;58(9 Pt 2):A121-5.
In order to clarify biochemical adaptation of the human body to short-term microgravity, metabolic and hormonal parameters were investigated in 20 cosmonauts who performed orbital flights of 4 to 14 d in duration. The specific feature of adaptation to this exposure is the transition to a new level of hormonal regulation with a significant increase of the content (production) of glucocorticoids, catecholamines, components of the renin-angiotensin-aldosterone system, which determines a modified activity of tissue hormones, and fluid-electrolyte homeostasis, as well as simultaneous increase of insulin secretion that diminishes the metabolic effects of glucocorticoids and catecholamines.
为了阐明人体对短期微重力的生化适应情况，对20名进行了4至14天轨道飞行的宇航员的代谢和激素参数进行了研究。适应这种暴露的具体特征是转变到激素调节的新水平，同时糖皮质激素、儿茶酚胺、肾素-血管紧张素-醛固酮系统各成分的含量（产生量）显著增加，这决定了组织激素的活性改变以及液体-电解质稳态，同时胰岛素分泌增加，减弱了糖皮质激素和儿茶酚胺的代谢作用。
