Tabeta Hiromitsu, Gunji Shizuka, Kawade Kensuke, Ferjani Ali
Department of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo, Tokyo, Japan.
Department of Biology, Tokyo Gakugei University, Tokyo, Japan.
Front Plant Sci. 2023 Jan 23;13:1024945. doi: 10.3389/fpls.2022.1024945. eCollection 2022.
Plant leaves display abundant morphological richness yet grow to characteristic sizes and shapes. Beginning with a small number of undifferentiated founder cells, leaves evolve a complex interplay of regulatory factors that ultimately influence cell proliferation and subsequent post-mitotic cell enlargement. During their development, a sequence of key events that shape leaves is both robustly executed spatiotemporally following a genomic molecular network and flexibly tuned by a variety of environmental stimuli. Decades of work on have revisited the compensatory phenomena that might reflect a general and primary size-regulatory mechanism in leaves. This review focuses on key molecular and cellular events behind the organ-wide scale regulation of compensatory mechanisms. Lastly, emerging novel mechanisms of metabolic and hormonal regulation are discussed, based on recent advances in the field that have provided insights into, among other phenomena, leaf-size regulation.
植物叶片呈现出丰富的形态多样性，但会生长到特定的大小和形状。从少量未分化的起始细胞开始，叶片演化出调节因子之间复杂的相互作用，这些调节因子最终影响细胞增殖以及随后的有丝分裂后细胞扩大。在叶片发育过程中，一系列塑造叶片的关键事件既按照基因组分子网络在时空上稳健地执行，又受到各种环境刺激的灵活调节。数十年来的研究重新审视了可能反映叶片中一种普遍且主要的大小调节机制的补偿现象。本综述聚焦于补偿机制在器官水平调节背后的关键分子和细胞事件。最后，基于该领域的最新进展，讨论了代谢和激素调节的新出现机制，这些进展为叶片大小调节等现象提供了深入见解。
