The present study aimed to characterize and assess the diversity of CoNS strains as potential vectors for the spread of resistance to antimicrobial agents from RTE foods served in bars and restaurants. Eighty-five CoNS strains, obtained from 198 RTE food samples, were investigated. Sixty-seven CoNS isolates (78.8%) were resistant to at least one antibiotic tested, and 37 (43.5%) were multidrug resistant (MDR-CoNS). Moreover, CoNS strains contained genes conferring resistance to antibiotics critically important in medicine, i.e., β-lactams [ (29.4%); (84.7%)], aminoglycosides [ (45.9%); (3.5%)], macrolides, lincosamides and streptogramin B-MLS [ (68.2%); (40%) and (4.7%)], tetracyclines [ (31.8%); (16.5%) and/or (2.35%)]. We also found the B/C/D genes responsible for the acquired low-level fusidic acid resistance (17.6%) and streptogramin resistance determinant in 30.6% of isolates. In three linezolid resistant strains (2 and 1 ), mutation was detected, as demonstrated by L101V and V188I changes in the L3 protein amino acid sequences. The high frequency in RTE food of MDR-CoNS including methicillin-resistant (MR-CoNS) strains constitutes a direct risk to public health as they increase the gene pool from which pathogenic bacteria can pick up resistance traits.