Department of Internal Medicine and Clinical Pharmacology, Medical University of Silesia, Medyków 18, 40-752 Katowice, Poland.
Private Health Care Center "ALFA-MED", Osiedle XXX-lecia 60, 44-386 Wodzisław Śląski, Poland.
Int J Environ Res Public Health. 2023 Jan 24;20(3):2122. doi: 10.3390/ijerph20032122.
Obesity, defined as body mass index (BMI) ≥ 30 kg/m, is one of the most important public health problems. Over one billion people are obese, including 650 million adults, which is 13% of the worldwide population, according to the World Health Organization (WHO). Similar to obesity, mental disorders such as depression and anxiety are huge social problems with serious health implications. There are numerous studies proving a strong link between the prevalence of obesity and depressive disorders, and being overweight is also associated with decreased health-related quality of life (HRQoL). Due to the broad negative impact of obesity on a patient's health, proper treatment is crucial. Currently, the literature describes many methods of treatment such as dietary treatment, pharmacotherapy using glucagon-like peptide-1 (GLP-1) analogs, orlistat, naltrexone/bupropion (NB), or finally bariatric surgery. The most commonly used methods of obesity treatment significantly improve the patient's quality of life and reduce the symptoms of depression and anxiety. The aim of our study was to summarize the knowledge about the impact of known and commonly used methods of obesity treatment (e.g., dietary treatment, bariatric surgery, and pharmacological treatment) on mental health and quality of life. For this purpose, we will try to review the current scientific data, originating from international reports.
肥胖定义为身体质量指数(BMI)≥30kg/m²,是最重要的公共卫生问题之一。根据世界卫生组织(WHO)的数据,全世界有超过 10 亿人肥胖,其中包括 6.5 亿成年人,占全球人口的 13%。与肥胖类似,抑郁和焦虑等精神障碍也是严重影响健康的巨大社会问题。有大量研究证明肥胖症的流行与抑郁障碍之间存在很强的关联,超重也与健康相关生活质量(HRQoL)下降有关。由于肥胖对患者健康的广泛负面影响,适当的治疗至关重要。目前,文献描述了许多治疗方法,如饮食治疗、使用胰高血糖素样肽-1(GLP-1)类似物、奥利司他、纳曲酮/安非他酮(NB)或最终进行减肥手术。最常用的肥胖症治疗方法可显著改善患者的生活质量,并减轻抑郁和焦虑症状。我们的研究旨在总结已知和常用的肥胖症治疗方法(例如饮食治疗、减肥手术和药物治疗)对心理健康和生活质量的影响。为此,我们将尝试审查源自国际报告的当前科学数据。