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基于釉质涂层的创新功能表面的抗菌性能:银基添加剂对抗菌和抗真菌活性的影响。

Antimicrobial Performance of Innovative Functionalized Surfaces Based on Enamel Coatings: The Effect of Silver-Based Additives on the Antibacterial and Antifungal Activity.

机构信息

Department of Cellular, Computational and Integrative Biology, University of Trento, 38123 Trento, Italy.

Department of Industrial Engineering, University of Trento, 38123 Trento, Italy.

出版信息

Int J Mol Sci. 2023 Jan 25;24(3):2364. doi: 10.3390/ijms24032364.

DOI:10.3390/ijms24032364
PMID:36768684
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9916675/
Abstract

Frequently touched surfaces (FTS) that are contaminated with pathogens are one of the main sources of nosocomial infections, which commonly include hospital-acquired and healthcare-associated infections (HAIs). HAIs are considered the most common adverse event that has a significant burden on the public's health worldwide currently. The persistence of pathogens on contaminated surfaces and the transmission of multi-drug resistant (MDR) pathogens by way of healthcare surfaces, which are frequently touched by healthcare workers, visitors, and patients increase the risk of acquiring infectious agents in hospital environments. Moreover, not only in hospitals but also in high-traffic public places, FTS play a major role in the spreading of pathogens. Consequently, attention has been devoted to developing novel and alternative methods to tackle this problem. This study planned to produce and characterize innovative functionalized enameled coated surfaces supplemented with 1% AgNO and 2% AgNO. Thus, the antimicrobial properties of the enamels against relevant nosocomial pathogens including the Gram-positive and the Gram-negative and the yeast were assessed using the ISO:22196:2011 norm.

摘要

经常接触的表面(FTS)如果被病原体污染,是医院感染的主要来源之一,通常包括医院获得性和与医疗保健相关的感染(HAIs)。HAIs 被认为是目前全球范围内对公众健康造成重大负担的最常见不良事件。病原体在污染表面上的持续存在以及医疗保健工作者、访客和患者经常接触的多药耐药(MDR)病原体通过医疗保健表面传播,增加了在医院环境中获得感染因子的风险。此外,不仅在医院,而且在高流量的公共场所,FTS 在病原体传播中也起着重要作用。因此,人们一直致力于开发新的替代方法来解决这个问题。本研究计划生产和表征具有创新性的功能化搪瓷涂层表面,补充 1%AgNO 和 2%AgNO。因此,使用 ISO:22196:2011 标准评估了搪瓷对相关医院病原体(包括革兰氏阳性菌和革兰氏阴性菌以及酵母)的抗菌性能。

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