Imperiale Ludovica, Nisolle Michelle, Noël Jean-Christophe, Fastrez Maxime
OB GYN Departement, ULB-Université Libre de Bruxelles, H.U.B.-Hôpital Universitaire de Bruxelles, CUB Hôpital Erasme, Route de Lennik 808, 1070 Brussels, Belgium.
Obstetrics and Gynecology Department, University of Liège, Boulevard du 12ème de Ligne 1, 4000 Liege, Belgium.
J Clin Med. 2023 Jan 28;12(3):994. doi: 10.3390/jcm12030994.
At present, there is no curative treatment for endometriosis. Medical management and surgical treatment do not provide long-term relief. A detailed understanding of its pathophysiology is mandatory in order to facilitate both the diagnosis and treatment. The delay that typically precedes proper diagnosis (6 to 7 years) is probably one of the most challenging aspects of endometriosis management. In 2012, the total cost per woman due to endometriosis was estimated to be 9579€ per year in a multicenter study across the USA and Europe. According to their physiopathology and their localization, ectopic endometrial lesions, consisting of endometrial glands and stroma, can be divided into three different types: superficial peritoneal endometriosis (SPE), ovarian endometrioma (OMA), and deep infiltrating endometriosis (DIE). The following paper aims to review the available data in the literature on the pathogenesis, diagnosis, and treatment of different types of endometriosis.
目前,子宫内膜异位症尚无治愈性治疗方法。药物治疗和手术治疗均无法提供长期缓解。为了便于诊断和治疗,必须详细了解其病理生理学。通常在正确诊断之前出现的延迟(6至7年)可能是子宫内膜异位症管理中最具挑战性的方面之一。2012年,在美国和欧洲进行的一项多中心研究中,估计每位女性每年因子宫内膜异位症产生的总成本为9579欧元。根据其病理生理学和定位,由子宫内膜腺体和间质组成的异位子宫内膜病变可分为三种不同类型:浅表性腹膜子宫内膜异位症(SPE)、卵巢子宫内膜异位囊肿(OMA)和深部浸润性子宫内膜异位症(DIE)。以下论文旨在综述文献中关于不同类型子宫内膜异位症的发病机制、诊断和治疗的现有数据。