Kallas Kadri-Ann, Marr Ketevan, Moirangthem Simi, Heude Barbara, Koehl Muriel, van der Waerden Judith, Downes Naomi
Social Epidemiology Research Team, Institut Pierre Louis d'Épidémiologie et de Santé Publique, INSERM U1136, Sorbonne Université, 75012 Paris, France.
Orchad Team, Epidemiology and Biostatistics Sorbonne Paris Cité Center, INSERM UMR1153, INRAE, Université de Paris, 75001 Paris, France.
J Clin Med. 2023 Jan 31;12(3):1120. doi: 10.3390/jcm12031120.
Few studies have investigated longitudinal trajectories of child socioemotional and behavioural development in relation to maternal prenatal mental health exposure or taken into consideration of the potential buffering effects of psychological intervention during pregnancy. Using data from 1135 mother-child dyads from the EDEN cohort from the general French population, Group-based trajectory modelling was used to model trajectories of behavioural and emotional characteristics measured at four timepoints via a parent-administered Strengths and Difficulties Questionnaire. Using propensity scores and inverse probability weighting to account for confounding factors, multinomial logistic regressions were used to quantify the associations with maternal symptoms of prenatal depression and anxiety. Stratified analyses were conducted by reporting psychologist and psychiatrist consultations during pregnancy. Compared to those without psychological problems, children of mothers with comorbid anxiety and depression retained a higher probability of following high and intermediate trajectories of emotional problems and a high trajectory of conduct problems throughout childhood. This increased risk was not present in the children of mothers who sought support through a prenatal psychologist or psychiatrist consultation. This article adds to a body of evidence underlining the importance of mental health care for expecting mothers.
很少有研究调查儿童社会情感和行为发展与母亲产前心理健康暴露之间的纵向轨迹,或者考虑孕期心理干预的潜在缓冲作用。利用来自法国普通人群EDEN队列的1135对母婴数据,基于群体的轨迹模型用于通过家长填写的优势与困难问卷对在四个时间点测量的行为和情绪特征轨迹进行建模。使用倾向得分和逆概率加权来考虑混杂因素,多项逻辑回归用于量化与产前抑郁和焦虑的母亲症状之间的关联。通过报告孕期咨询心理医生和精神科医生的情况进行分层分析。与没有心理问题的母亲的孩子相比,患有焦虑和抑郁合并症的母亲的孩子在整个童年期出现情绪问题的高轨迹和中轨迹以及行为问题的高轨迹的可能性更高。在通过产前咨询心理医生或精神科医生寻求支持的母亲的孩子中,这种风险增加并不存在。本文补充了一系列强调为准妈妈提供心理健康护理重要性的证据。