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纳米锌在禽类和生物医药领域应用的机制方法:未来展望和挑战的综合评述。

Mechanistic Approaches to the Application of Nano-Zinc in the Poultry and Biomedical Industries: A Comprehensive Review of Future Perspectives and Challenges.

机构信息

Department of Botany, Pir Mehr Ali Shah (PMAS)-Arid Agriculture University, Rawalpindi 46300, Pakistan.

Department of Botany, University of Malakand, Chakdara 18800, Pakistan.

出版信息

Molecules. 2023 Jan 20;28(3):1064. doi: 10.3390/molecules28031064.

Abstract

Bio-fortification is a new, viable, cost-effective, and long-term method of administering crucial minerals to a populace with limited exposure to diversified foods and other nutritional regimens. Nanotechnology entities aid in the improvement of traditional nutraceutical absorption, digestibility, and bio-availability. Nano-applications are employed in poultry systems utilizing readily accessible instruments and processes that have no negative impact on animal health and welfare. Nanotechnology is a sophisticated innovation in the realm of biomedical engineering that is used to diagnose and cure various poultry ailments. In the 21st century, zinc nanoparticles had received a lot of considerable interest due to their unusual features. ZnO NPs exhibit antibacterial properties; however, the qualities of nanoparticles (NPs) vary with their size and structure, rendering them adaptable to diverse uses. ZnO NPs have shown remarkable promise in bio-imaging and drug delivery due to their high bio-compatibility. The green synthesized nanoparticles have robust biological activities and are used in a variety of biological applications across industries. The current review also discusses the formulation and recent advancements of zinc oxide nanoparticles from plant sources (such as leaves, stems, bark, roots, rhizomes, fruits, flowers, and seeds) and their anti-cancerous activities, activities in wound healing, and drug delivery, followed by a detailed discussion of their mechanisms of action.

摘要

生物强化是一种新的、可行的、具有成本效益的、长期的方法,可以向接触多样化食物和其他营养方案有限的人群提供关键矿物质。纳米技术实体有助于改善传统的营养吸收、消化率和生物利用度。纳米应用在利用易于获得的仪器和工艺的家禽系统中得到了应用,这些仪器和工艺对动物的健康和福利没有负面影响。纳米技术是生物医学工程领域的一项复杂创新,用于诊断和治疗各种家禽疾病。在 21 世纪,由于其独特的特性,锌纳米粒子受到了广泛关注。氧化锌纳米粒子具有抗菌特性;然而,纳米粒子的特性(NPs)因尺寸和结构而异,使其能够适应多种用途。由于其高生物相容性,氧化锌纳米粒子在生物成像和药物传递方面显示出了显著的前景。绿色合成的纳米粒子具有强大的生物活性,并在各个行业的各种生物应用中得到了应用。本综述还讨论了植物来源(如叶、茎、皮、根、根茎、果实、花和种子)合成的氧化锌纳米粒子的配方和最新进展,以及它们的抗癌活性、在伤口愈合和药物传递方面的应用,并详细讨论了它们的作用机制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd1f/9921179/ca2a322c448a/molecules-28-01064-g001.jpg

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