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一种用于预测甲状腺功能减退症的新型布隆智能特征分类模型。

A Novel Blunge Calibration Intelligent Feature Classification Model for the Prediction of Hypothyroid Disease.

机构信息

Department of CSE, Vel Tech Rangarajan Dr. Sagunthala R&D Institute of Science and Technology, Chennai 600062, India.

Faculty of Electronics, Telecommunications and Information Technology, "Gheorghe Asachi" Tehnical University, 700506 Iasi, Romania.

出版信息

Sensors (Basel). 2023 Jan 18;23(3):1128. doi: 10.3390/s23031128.

Abstract

According to the Indian health line report, 12% of the population suffer from abnormal thyroid functioning. The major challenge in this disease is that the existence of hypothyroid may not propagate any noticeable symptoms in its early stages. However, delayed treatment of this disease may lead to several other health problems, such as fertility issues and obesity. Therefore, early treatment is essential for patient survival. The proposed technology could be used for the prediction of hypothyroid disease and its severity during its early stages. Though several classification and regression algorithms are available for the prediction of hypothyroid using clinical information, there exists a gap in knowledge as to whether predicted outcomes may reach a higher accuracy or not. Therefore, the objective of this research is to predict the existence of hypothyroidism with higher accuracy by optimizing the estimator list of the pycaret classifier model. With this overview, a blunge calibration intelligent feature classification model that supports the assessment of the presence of hypothyroidism with high accuracy is proposed. A hypothyroidism dataset containing 3163 patient details with 23 independent and one dependent feature from the University of California Irvine (UCI) machine-learning repository was used for this work. We undertook dataset preprocessing and determined its incomplete values. Exploratory data analysis was performed to analyze all the clinical parameters and the extent to which each feature supports the prediction of hypothyroidism. ANOVA was used to verify the F-statistic values of all attributes that might highly influence the target. Then, hypothyroidism was predicted using various classifier algorithms, and the performance metrics were analyzed. The original dataset was subjected to dimensionality reduction by using regressor and classifier feature-selection algorithms to determine the best subset components for predicting hypothyroidism. The feature-selected subset of the clinical parameters was subjected to various classifier algorithms, and its performance was analyzed. The system was implemented with python in the Spyder editor of Anaconda Navigator IDE. Investigational results show that the Gaussian naive Bayes, AdaBoost classifier, and Ridge classifier maintained the accuracy of 89.5% for the regressor feature-selection methods. The blunge calibration regression model (BCRM) was designed with naive Bayes, AdaBoost, and Ridge as the estimators with accuracy optimization and with soft blending based on the sum of predicted probabilities of classifiers. The proposed BCRM showed 99.5% accuracy in predicting hypothyroidism. The implementation results show that the Kernel SVM, KNeighbor, and Ridge classifier maintained an accuracy of 87.5% for the classifier feature-selection methods. The blunge calibration classifier model (BCCM) was developed with Kernel SVM, KNeighbor, and Ridge as the estimators, with accuracy optimization and with soft blending based on the sum of predicted probabilities of classifiers. The proposed BCCM showed 99.7% accuracy in predicting hypothyroidism. The main contribution of this research is the design of BCCM and BCRM models that were built with accuracy optimization with soft blending based on the sum of predicted probabilities of classifiers. The BCRM and BCCM models uniqueness's are achieved by updating the estimators list with the effective classifiers and regressors that suit the application at runtime.

摘要

根据印度健康热线报告,有 12%的人口患有甲状腺功能异常。这种疾病的主要挑战在于,甲状腺功能减退在早期可能不会出现任何明显的症状。然而,这种疾病的延迟治疗可能会导致其他一些健康问题,如生育问题和肥胖。因此,早期治疗对患者的生存至关重要。所提出的技术可用于在早期预测甲状腺功能减退症及其严重程度。尽管有几种分类和回归算法可用于使用临床信息预测甲状腺功能减退,但尚不清楚预测结果是否可以达到更高的准确性。因此,本研究的目的是通过优化 pycaret 分类器模型的估计器列表来更准确地预测甲状腺功能减退的存在。通过这一概述,提出了一种 blunge 校准智能特征分类模型,用于支持对甲状腺功能减退的存在进行高精度评估。这项工作使用了来自加利福尼亚大学欧文分校(UCI)机器学习存储库的包含 3163 名患者详细信息的甲状腺功能减退数据集,其中包含 23 个独立特征和一个依赖特征。我们进行了数据集预处理,并确定了其不完整的值。进行了探索性数据分析,以分析所有临床参数以及每个特征支持甲状腺功能减退预测的程度。使用方差分析来验证可能对目标有高度影响的所有属性的 F-统计值。然后,使用各种分类器算法预测甲状腺功能减退,并分析性能指标。使用回归器和分类器特征选择算法对原始数据集进行降维,以确定预测甲状腺功能减退的最佳子集组件。将临床参数的特征选择子集应用于各种分类器算法,并分析其性能。该系统使用 python 在 Anaconda Navigator IDE 的 Spyder 编辑器中实现。研究结果表明,对于回归器特征选择方法,高斯朴素贝叶斯、AdaBoost 分类器和 Ridge 分类器保持了 89.5%的准确性。设计了基于朴素贝叶斯、AdaBoost 和 Ridge 的 blunge 校准回归模型(BCRM)作为估计器,并基于分类器预测概率之和进行了准确性优化和软混合。所提出的 BCRM 在预测甲状腺功能减退方面的准确率达到了 99.5%。实现结果表明,对于分类器特征选择方法,核支持向量机、KNeighbor 和 Ridge 分类器保持了 87.5%的准确性。设计了基于核支持向量机、KNeighbor 和 Ridge 的 blunge 校准分类模型(BCCM)作为估计器,并基于分类器预测概率之和进行了准确性优化和软混合。所提出的 BCCM 在预测甲状腺功能减退方面的准确率达到了 99.7%。本研究的主要贡献是设计了 BCCM 和 BCRM 模型,这些模型通过基于分类器预测概率之和的软混合进行了准确性优化。BCRM 和 BCCM 模型的独特性是通过在运行时使用适合应用的有效分类器和回归器更新估计器列表来实现的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e61/9922023/1d141b142ff4/sensors-23-01128-g001.jpg

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