Ansley D M, Ramsay J G, Whalley D G, Bent J M, Lisbona R, Derbekyan V, Wynands J E
Department of Anaesthesia, Royal Victoria Hospital, Montreal, Quebec.
Can J Anaesth. 1987 Nov;34(6):594-600. doi: 10.1007/BF03010518.
Twenty-three ASA physical status II-III patients scheduled for elective abdominal aortic surgery were studied preoperatively with multiple unit gated acquisition angiography (MUGA) scan to determine the resting left ventricular and right ventricular ejection fractions (LVEF and RVEF respectively). Intraoperatively pulmonary capillary wedge pressure (PCWP) and central venous pressure (CVP) were measured in each patient at five different time periods in the horizontal, 24 degrees head up, and 24 degrees head down table tilt positions. The correlation between absolute values and changes in PCWP and CVP, and the degree to which preoperative knowledge of LVEF and RVEF predicted these correlations were examined. Resting LVEF ranged from 0.1 to 0.84. Thirteen of the 23 patients failed to show significant correlation (p less than 0.05) between the absolute values of PCWP and CVP either before and/or after aortic crossclamp. When the correlation coefficients from this analysis were ranked against LVEF, there was a weak but significant correlation before aortic crossclamp (r = 0.41), but not after. The correlation between a change in PCWP and a change in CVP was significant for the 23 patients at all time intervals, before and after aortic crossclamp. However, the prediction of a change of PCWP value from a known change of CVP value ranged in accuracy from +/- 3 mmHg to +/- 12.5 mmHg. The study suggests that if the filling pressures of both ventricles need to be assessed during aortic surgery, then the PCWP and CVP must be independently measured.(ABSTRACT TRUNCATED AT 250 WORDS)
对23例计划行择期腹主动脉手术的美国麻醉医师协会(ASA)身体状况II-III级患者,术前采用多门控采集血管造影(MUGA)扫描,以确定静息状态下的左心室和右心室射血分数(分别为LVEF和RVEF)。术中在水平位、头高位24度和头低位24度的手术台倾斜位置的五个不同时间段,测量每位患者的肺毛细血管楔压(PCWP)和中心静脉压(CVP)。研究了PCWP和CVP绝对值及变化之间的相关性,以及术前LVEF和RVEF的了解程度对这些相关性的预测能力。静息LVEF范围为0.1至0.84。23例患者中有13例在主动脉阻断前后,PCWP和CVP绝对值之间未显示出显著相关性(p<0.05)。当将该分析的相关系数与LVEF进行排序时,主动脉阻断前存在弱但显著的相关性(r = 0.41),但阻断后则无。在主动脉阻断前后的所有时间间隔内,23例患者PCWP变化与CVP变化之间的相关性均显著。然而,根据已知的CVP值变化预测PCWP值变化的准确性范围为±3 mmHg至±12.5 mmHg。该研究表明,如果在主动脉手术期间需要评估两个心室的充盈压力,则必须独立测量PCWP和CVP。(摘要截断于250字)