Refractive Surgery Center, Chongqing Eye and Vision Care Hospital, Yuzhong District, NO.77, the second Changjiang Road, Chongqing, China.
BMC Ophthalmol. 2023 Feb 11;23(1):61. doi: 10.1186/s12886-022-02713-3.
Toxic anterior segment syndrome (TASS) is a non-infectious inflammation that can occur after any anterior segment procedure. This case report presents two relatively rare late-onset TASS cases after V4c implantable collamer lens (ICL) operation.
One 25-year-old woman and one 31-year-old woman suddenly had vision loss in monocular for 1 week after biocular V4c ICL operations and with no subjective complaints. They both presented fibrin formation in the anterior chamber such as keratic precipitates and white pus on the surface of the ICL. Fundus examination was normal. After 4 to 5 weeks of topical and oral steroid treatment, visual acuity and fibrin formation in the anterior chamber improved during the follow-up.
TASS should be suspected in any patient during the late period following ICL surgery; Once TASS is diagnosed, adequate treatment with intensive steroid therapy can be implemented.
毒性前节综合征（TASS）是一种非传染性炎症，可发生在任何前节手术后。本病例报告介绍了 V4c 可植入Collamer 透镜（ICL）手术后两种相对罕见的迟发性 TASS 病例。
一名 25 岁女性和一名 31 岁女性在双眼 V4c ICL 手术后 1 周内突然出现单眼视力丧失，无主观主诉。两人均在前房出现纤维蛋白形成，如角膜沉淀物和 ICL 表面的白色脓液。眼底检查正常。经过 4 至 5 周的局部和口服类固醇治疗，随访期间视力和前房纤维蛋白形成有所改善。
在 ICL 手术后的晚期，任何患者都应怀疑 TASS；一旦诊断出 TASS，可采用强化类固醇治疗进行充分治疗。
