埃及私有犬猫中巴尔通体属、嗜血性支原体属及其他媒介传播病原体的流行情况

Prevalence of Bartonella spp., haemotropic Mycoplasma spp. and others vector-borne pathogens in private-owned dogs and cats, Egypt.

作者信息

Zarea A A K, Tempesta M, Fouad E A, Ndiana L A, Mahmoud M S, Mrenoshki D, Martella V, Decaro N, Chomel B, Greco G

机构信息

Department of Veterinary Medicine, University of Bari Aldo Moro, Bari, Italy; Department of Microbiology and Immunology, Veterinary Research Institute, National Research Centre (NRC), Cairo, Egypt.

Department of Veterinary Medicine, University of Bari Aldo Moro, Bari, Italy.

出版信息

Acta Trop. 2023 Apr;240:106857. doi: 10.1016/j.actatropica.2023.106857. Epub 2023 Feb 10.

DOI:10.1016/j.actatropica.2023.106857

PMID:36775003

Abstract

Vector-borne pathogens have been increasingly investigated for their impact on dog and cat health and their zoonotic potential. The aim of this study was to investigate the prevalence estimates of selected vector-borne pathogens in client-owned pets from the Giza and Cairo governorates, Egypt. Out of 200 dogs and 100 cats, 94 (47%) and 23 (23%) were positive for at least one of the tested pathogens (P<0.0001). In particular, 84 (42%) dogs and 3 (3%) cats tested PCR-positive for Bartonella spp. (P<0.0001). A significantly higher prevalence of Bartonella spp. was detected in dogs from the rural areas of the Giza governorate (60/77, 79.2%, P<0.0001) compared to those from Cairo governorate. Bartonella henselae was the dominant species infecting dogs (81/200, 40.5%) followed by Candidatus Bartonella merieuxii (3/200, 1.5%), while B. henselae (2/100, 2%) and B. clarridgeiae were rare in cats. Haemoplasma DNA was detected in 17% (34/200) of dogs and 20% (20/100) of cats with increased risk in dogs from Giza rural areas (21/77, 27.27%, P=0.002) and from both dogs (16/63, 25.40%, P=0.03) and cats (7/14, 50%, P<0.002) with anemia. Candidatus Mycoplasma haematoparvum (30/200, 15%) and Mycoplasma haemocanis (4/200, 2%) in dogs and Candidatus Mycoplasma haemominutum (18/100, 18%) and M. haemofelis (2/100, 2%) in cats were detected. Additionally, 2 dogs were positive for C. burnetii DNA. Coinfections were detected in dogs, with the majority (23/200, 11.5%) including B. henselae and C.M. haematoparvum, followed by Mycoplasma haemocanis and C.M. haematoparvum (2/200, 1%) and B. henselae, CMhp and C. burnetii (2/200, 1%). Haemoplasma infection was high in Egyptian dogs and cats with a high prevalence for zoonotic Bartonella spp. in dogs with anemia, highlighting the need to investigate these agents in the diagnostic algorithm of anemia and to adopt preventive measures to protect both animal and human health.

摘要

媒介传播病原体对犬猫健康的影响及其人畜共患病潜力日益受到关注。本研究旨在调查埃及吉萨省和开罗省宠物诊所中选定媒介传播病原体的流行率。在200只狗和100只猫中，分别有94只（47%）和23只（23%）至少对一种检测病原体呈阳性（P<0.0001）。具体而言，84只（42%）狗和3只（3%）猫经PCR检测巴尔通体属呈阳性（P<0.0001）。与开罗省的狗相比，在吉萨省农村地区的狗中检测到巴尔通体属的流行率显著更高（60/77，79.2%，P<0.0001）。亨氏巴尔通体是感染狗的主要菌种（81/200，40.5%），其次是马赛巴尔通体（3/200，1.5%），而亨氏巴尔通体（2/100，2%）和克拉氏巴尔通体在猫中较为罕见。在17%（34/200）的狗和20%（20/100）的猫中检测到血巴尔通体DNA，来自吉萨农村地区的狗感染风险增加（21/77，27.27%，P=0.002），贫血的狗（16/63，25.40%，P=0.03）和猫（7/14，50%，P<0.002）中感染风险也增加。在狗中检测到微小血支原体（30/200，15%）和犬血支原体（4/200，2%），在猫中检测到溶血微小支原体（18/100，18%）和溶血支原体（2/100,2%）。此外，2只狗的伯氏柯克斯体DNA呈阳性。在狗中检测到混合感染，大多数（23/200，11.5%）包括亨氏巴尔通体和微小血支原体，其次是犬血支原体和微小血支原体（2/200，1%）以及亨氏巴尔通体、微小血支原体和伯氏柯克斯体（2/200，1%）。埃及的狗和猫血巴尔通体感染率较高，贫血犬中具有人畜共患潜力的巴尔通体属流行率较高，这突出表明有必要在贫血诊断算法中对这些病原体进行调查，并采取预防措施保护动物和人类健康。