Chemistry Laboratory, Department of Chemistry, Faculty of Science, University of Douala, Douala, Cameroon.
University Institute of Technology, University of Ngaoundere, Ngaoundere, Cameroon.
Nat Prod Res. 2023 Nov-Dec;37(24):4188-4198. doi: 10.1080/14786419.2023.2177287. Epub 2023 Feb 12.
The chemical investigation of the methanolic root extract of led to the isolation of a new arylbenzoate derivative, vogelinal (), together with thirteen known compounds (). The structures of the isolates were elucidated by extensive spectroscopic and spectrometric analyses (1D and 2D NMR, ESI-MS) and by comparison with previously reported data. All the compounds were tested for their antioxidant, antifungal and antibacterial activities. Compound exhibited the highest antioxidant potential, with RSaof 11.80 ± 2.13 µg/mL, RSaof 42.60 ± 6.32 µg/mL and RC of 51.60 ± 7.71 µg/mL for the DPPH, ABTS and FRAP assay, respectively. Compound displayed weak antifungal effect with MIC value of 125 μg/mL against . Compound showed weak antibacterial effect with MIC value of 125 μg/mL, against . The present study, conclude that this species could be a promising source of antioxidant and antibacterial constituents.
对 led 的甲醇根提取物的化学研究导致了一种新的芳基苯甲酸酯衍生物 vogelinal()的分离，以及十三种已知化合物()。通过广泛的光谱和光谱分析(1D 和 2D NMR、ESI-MS)以及与先前报道的数据进行比较，确定了分离物的结构。所有化合物均进行了抗氧化、抗真菌和抗菌活性测试。化合物()表现出最高的抗氧化潜力，其 DPPH、ABTS 和 FRAP 测定的 RSA 分别为 11.80±2.13μg/mL、42.60±6.32μg/mL 和 RC 为 51.60±7.71μg/mL。化合物()对 显示出较弱的抗真菌作用，MIC 值为 125μg/mL。化合物()对 显示出较弱的抗菌作用，MIC 值为 125μg/mL。本研究表明，该种可能是抗氧化和抗菌成分的有前途的来源。
