Thoddi Ramamurthy Muralidharan, Kumar Balakrishnan Vinod, Sunny Sini, Rajkumar Abinayaa, Sundaram Sandhya, Krishnamurthy Preetam, Boopathy Senguttuvan Nagendra, Murali Arunan, Santhosham J D Roy, Periandavan Kalaiselvi, Rajasekaran Namakkal S
Department of Cardiology, Sri Ramachandra Medical University and Research Institute, Chennai, Tamil Nadu, India.
Division of Molecular and Cellular Pathology, Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, United States.
Front Cardiovasc Med. 2023 Jan 26;9:1046436. doi: 10.3389/fcvm.2022.1046436. eCollection 2022.
The reported incidence of liposarcomas in ~2,000 cases annually results in about 30% of myxoid liposarcomas. Cardiac myoxid liposarcomas are very rare; their presentation could be cardiac tamponade, due to direct compression of the tumor and/or pericardial effusion. In this report, we describe a patient who presented with pericardial effusion secondary to myoxid liposarcomas from the right atrium, an extremely rare presentation of liposarcomas in the heart. We also present non-invasive imaging through echocardiography, CECT thorax and FDG PET scans, followed by a CT-guided mass biopsy. Histopathology of the right atrial mass demonstrated myxoid liposarcoma positive for the S100 tumor marker.
据报道，每年约2000例脂肪肉瘤病例中，黏液样脂肪肉瘤约占30%。心脏黏液样脂肪肉瘤非常罕见；其表现可能为心脏压塞，原因是肿瘤直接压迫和/或心包积液。在本报告中，我们描述了一名因右心房黏液样脂肪肉瘤继发心包积液的患者，这是脂肪肉瘤在心脏中极为罕见的表现。我们还展示了通过超声心动图、胸部CT增强扫描和氟代脱氧葡萄糖正电子发射断层扫描进行的无创成像，随后进行了CT引导下的肿块活检。右心房肿块的组织病理学检查显示黏液样脂肪肉瘤，S100肿瘤标志物呈阳性。
