Lambrechts Mark J, Toci Gregory R, Karamian Brian A, Kozick Zachary, Prodoehl John, Reiter David, Muchintala Rahul, Tecce Eric, Vaccaro Alexander, O'Connor Patrick, Syal Amit, Lambo Dominic, Canseco Jose A, Kaye I David, Woods Barrett I, Hilibrand Alan S, Kepler Christopher K, Vaccaro Alexander R, Schroeder Gregory D
Department of Orthopaedic Surgery, Rothman Institute, Thomas Jefferson University, Philadelphia, PA, USA.
J Craniovertebr Junction Spine. 2022 Oct-Dec;13(4):415-420. doi: 10.4103/jcvjs.jcvjs_100_22. Epub 2022 Dec 7.
The study design used was a retrospective cohort.
The objective of this study is to determine if intraoperative improvements in sagittal alignment on the operating table persisted on postoperative standing radiographs.
Cervical sagittal alignment may be correlated to postoperative outcomes. Since anterior cervical discectomy and fusions (ACDFs) can restore some cervical lordosis through intervertebral grafts/cages, it is important to understand if intraoperative radiographic measurements correlate with persistent postoperative radiographic changes.
Patients undergoing elective primary ACDF were screened for the presence of lateral cervical radiographs preoperatively, intraoperatively, and postoperatively. Patients were excluded if their first postoperative radiograph was more than 3 months following the procedure or if cervical lordosis was not able to be measured at each time point. Paired -tests were utilized to compare differences in measurements between time points. Statistical significance was set at < 0.05.
Of 46 included patients, 26 (56.5%) were female, and the mean age was 55.2 ± 11.6 years. C0-C2 lordosis significantly increased from the preoperative to intraoperative time point (delta [Δ] = 4.49, = 0.029) and significantly decreased from the intraoperative to postoperative time period (Δ = -6.57, < 0.001), but this resulted in no significant preoperative to postoperative change (Δ = -2.08, = 0.096). C2 slope decreased from the preoperative to the intraoperative time point (Δ = -3.84, = 0.043) and significantly increased from the intraoperative to the postoperative time point (Δ = 3.68, = 0.047), which also resulted in no net change in alignment between the preoperative and postoperative periods (Δ = -0.16, = 0.848). There was no significant difference in the C2-C7 SVA from the preoperative to intraoperative (Δ = 0.85, = 0.724) or intraoperative to postoperative periods (Δ = 2.04, = 0.401); however, the C2-C7 SVA significantly increased from the preoperative to postoperative period (Δ = 2.88, = 0.006).
Intraoperative positioning predominantly affects the mobile upper cervical spine, particularly C0-C2 lordosis and C2 slope, but these changes do not persist postoperatively.
本研究采用回顾性队列研究。
本研究的目的是确定手术台上矢状面排列的术中改善情况在术后站立位X线片上是否持续存在。
颈椎矢状面排列可能与术后结果相关。由于颈椎前路椎间盘切除融合术(ACDF)可通过椎间植骨/椎间融合器恢复一定的颈椎前凸,因此了解术中影像学测量结果与术后持续的影像学变化是否相关很重要。
对接受择期初次ACDF手术的患者术前、术中及术后的颈椎侧位X线片进行筛查。如果患者术后第一张X线片距离手术超过3个月,或者在每个时间点均无法测量颈椎前凸,则将其排除。采用配对t检验比较各时间点测量值的差异。设定统计学显著性水平为P<0.05。
纳入的46例患者中,26例(56.5%)为女性,平均年龄为55.2±11.6岁。C0-C2前凸从术前到术中时间点显著增加(差值[Δ]=4.49,P=0.029),从术中到术后时间点显著降低(Δ=-6.57,P<0.001),但术前到术后无显著变化(Δ=-2.08,P=0.096)。C2斜率从术前到术中时间点降低(Δ=-3.84,P=0.043),从术中到术后时间点显著增加(Δ=3.68,P=0.047),术前和术后之间的排列也无净变化(Δ=-0.16,P=0.848)。C2-C7矢状面垂直轴(SVA)从术前到术中(Δ=0.85,P=0.724)或术中到术后(Δ=2.04,P=0.401)无显著差异;然而,C2-C7 SVA从术前到术后显著增加(Δ=2.88,P=0.006)。
术中定位主要影响活动度较大的上颈椎,尤其是C0-C2前凸和C2斜率,但这些变化术后未持续存在。