富血小板纤维蛋白在增强牙种植体稳定性方面的临床应用：一项系统评价和荟萃分析。
Clinical application of platelet-rich fibrin to enhance dental implant stability: A systematic review and meta-analysis.
作者信息
Guan Shuai, Xiao Tiepeng, Bai Jiuping, Ning Chunliu, Zhang Xingkui, Yang Lei, Li Xiangjun
机构信息
Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Hebei Medical University and Hebei Key Laboratory of Stomatology, Shijiazhuang, 050017, PR China.
The Second Affiliated Hospital of Hebei Medical University, Shijiazhuang, 050000, PR China.
出版信息
Heliyon. 2023 Jan 26;9(2):e13196. doi: 10.1016/j.heliyon.2023.e13196. eCollection 2023 Feb.
OBJECTIVE
To investigate the effect of platelet-rich fibrin application on implant stability.
STUDY DESIGN
Five databases, namely, PubMed, Embase, Web of Science, Wiley, and China National Knowledge Infrastructure, were searched for reports published up to November 20, 2022. Randomized controlled trials (RCT), including parallel RCTs and split-mouth RCTs, with at least 10 patients/sites were considered for inclusion.
RESULTS
After screening based on the inclusion criteria, ten RCTs were included. Low heterogeneity was observed in study characteristics, outcome variables, and estimation scales (I = 27.2%, P = 0.19). The qualitative and meta-analysis results showed that PRF increased the effect of implant stabilizers after implant surgery.
CONCLUSIONS
The results of the present systematic review and meta-analysis suggest that PRF can increase implant stability after implant surgery. PRF may also have a role in accelerating bone healing and tends to promote new bone formation at the implant site.
目的
探讨富血小板纤维蛋白应用对种植体稳定性的影响。
研究设计
检索了五个数据库，即PubMed、Embase、Web of Science、Wiley和中国知网，以查找截至2022年11月20日发表的报告。纳入至少有10例患者/部位的随机对照试验（RCT），包括平行RCT和分口RCT。
结果
根据纳入标准筛选后，纳入了10项RCT。在研究特征、结局变量和评估量表方面观察到低异质性（I=27.2%，P=0.19）。定性和荟萃分析结果表明，富血小板纤维蛋白在种植手术后增强了种植体稳定器的效果。
结论
本系统评价和荟萃分析结果表明，富血小板纤维蛋白可提高种植手术后的种植体稳定性。富血小板纤维蛋白在加速骨愈合方面可能也有作用，并且倾向于促进种植部位的新骨形成。
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