Children's Hospital Westmead Clinical School, The University of Sydney, Westmead, New South Wales2145, Australia.
Charles Perkins Centre, The University of Sydney, Sydney, New South Wales2145, Australia.
Nutr Res Rev. 2024 Jun;37(1):32-42. doi: 10.1017/S0954422423000045. Epub 2023 Feb 15.
The cornerstone of obesity treatment is behavioural weight management, resulting in significant improvements in cardio-metabolic and psychosocial health. However, there is ongoing concern that dietary interventions used for weight management may precipitate the development of eating disorders. Systematic reviews demonstrate that, while for most participants medically supervised obesity treatment improves risk scores related to eating disorders, a subset of people who undergo obesity treatment may have poor outcomes for eating disorders. This review summarises the background and rationale for the formation of the Eating Disorders In weight-related Therapy (EDIT) Collaboration. The EDIT Collaboration will explore the complex risk factor interactions that precede changes to eating disorder risk following weight management. In this review, we also outline the programme of work and design of studies for the EDIT Collaboration, including expected knowledge gains. The EDIT studies explore risk factors and the interactions between them using individual-level data from international weight management trials. Combining all available data on eating disorder risk from weight management trials will allow sufficient sample size to interrogate our hypothesis: that individuals undertaking weight management interventions will vary in their eating disorder risk profile, on the basis of personal characteristics and intervention strategies available to them. The collaboration includes the integration of health consumers in project development and translation. An important knowledge gain from this project is a comprehensive understanding of the impact of weight management interventions on eating disorder risk.
肥胖治疗的基石是行为体重管理，这可以显著改善心血管代谢和心理社会健康。然而，人们一直担心用于体重管理的饮食干预可能会引发饮食失调。系统评价表明，虽然对于大多数参与者来说，医学监督的肥胖治疗可以改善与饮食失调相关的风险评分，但一部分接受肥胖治疗的人可能会出现饮食失调的不良后果。本文总结了成立饮食失调与体重相关治疗（EDIT）合作组织的背景和基本原理。EDIT 合作组织将探讨在体重管理后饮食失调风险变化之前的复杂风险因素相互作用。在本文中，我们还概述了 EDIT 合作组织的工作计划和研究设计，包括预期的知识收益。EDIT 研究使用国际体重管理试验中的个体水平数据来探索风险因素及其相互作用。合并体重管理试验中关于饮食失调风险的所有可用数据，将允许有足够的样本量来检验我们的假设：即接受体重管理干预的个体在基于个人特征和可获得的干预策略的情况下，其饮食失调风险特征会有所不同。该合作组织包括将健康消费者纳入项目开发和转化中。该项目的一个重要知识收益是全面了解体重管理干预对饮食失调风险的影响。
