Bawazeer Amani, Rahali Wejdan, Alsharif Alhanouf, Alshehri Malak, Maksood Lama, Babkier Ahad, Hommadi Walaa, Othman Basant, Omair Mohammed A, Hafiz Waleed A
Department of Medicine, Alnoor Specialist Hospital, Makkah, SAU.
College of Medicine, Umm Al-Qura University, Makkah, SAU.
Cureus. 2023 Jan 10;15(1):e33614. doi: 10.7759/cureus.33614. eCollection 2023 Jan.
Idiopathic orbital inflammation is a benign condition that affects the orbit and the extra-orbital structures. It presents as ocular pain, peri-orbital swelling, proptosis, and restricted ocular movements. This condition is diagnosed based on clinical features that are then confirmed by radiological and histopathological findings. Corticosteroids are the initial therapy of choice. Disease-modifying antirheumatic drugs are added in steroid non-responsive patients. Rituximab is now becoming increasingly used as a third-line therapy for this disease. We report a case of idiopathic orbital inflammation treated with rituximab monotherapy without the use of corticosteroids or disease-modifying antirheumatic drugs.
特发性眼眶炎症是一种影响眼眶和眶外结构的良性疾病。其表现为眼痛、眶周肿胀、眼球突出和眼球运动受限。该疾病根据临床特征进行诊断，随后通过放射学和组织病理学检查结果得以证实。皮质类固醇是首选的初始治疗方法。对于对类固醇无反应的患者，会加用改善病情的抗风湿药物。利妥昔单抗现在越来越多地被用作该疾病的三线治疗药物。我们报告一例特发性眼眶炎症患者，采用利妥昔单抗单药治疗，未使用皮质类固醇或改善病情的抗风湿药物。
