Nikparast Ali, Sheikhhossein Fatemeh, Amini Mohammad Reza, Tavakoli Sogand, Hekmatdoost Azita
Student Research Committee, Department of Clinical Nutrition and Dietetics, Faculty of Nutrition Sciences and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran 198396-3113, Iran.
Department of Clinical Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences (TUMS), Tehran 14155-6117, Iran.
Clin Nutr Res. 2023 Jan 17;12(1):54-64. doi: 10.7762/cnr.2023.12.1.54. eCollection 2023 Jan.
A systematic review and meta-analysis were designed to summarize studies conducted on the effects of raspberry and blackcurrant consumption on blood pressure (BP). Eligible studies were detected by searching numerous five online databases including PubMed, Scopus, Web of Science, Cochrane Library, and Google Scholar, until December 17, 2022. We pooled the mean difference and its 95% confidence interval (CI) by applying a random-effects model. Overall, the impact of raspberry and blackcurrant on BP was reported in ten randomized controlled trials (RCTs) (420 subjects). Pooled analysis of six clinical trials revealed that raspberry consumption has no significant reduction in systolic blood pressure (SBP) (weighted mean differences [WMDs], -1.42; 95% CI, -3.27 to 0.87; p = 0.224) and diastolic blood pressure (DBP) (WMD, -0.53; 95% CI, -1.77 to 0.71; p = 0.401), in comparison with placebo. Moreover, pooled analysis of four clinical trials indicated that blackcurrant consumption did not reduce SBP (WMD, -1.46; 95% CI, -6.62 to 3.7; p = 0.579), and DBP (WMD, -2.09; 95% CI, -4.38 to 0.20; p = 0.07). Raspberry and blackcurrant consumption elicited no significant reductions in BP. More accurate RCTs are required to clarify the impact of raspberry and blackcurrant intake on BP.
一项系统评价和荟萃分析旨在总结关于食用树莓和黑加仑对血压(BP)影响的研究。通过检索包括PubMed、Scopus、科学网、考克兰图书馆和谷歌学术在内的五个在线数据库,直至2022年12月17日,筛选出符合条件的研究。我们采用随机效应模型汇总平均差及其95%置信区间(CI)。总体而言,十项随机对照试验(RCT)(420名受试者)报告了树莓和黑加仑对血压的影响。六项临床试验的汇总分析显示,与安慰剂相比,食用树莓对收缩压(SBP)无显著降低作用(加权平均差[WMDs],-1.42;95%CI,-3.27至0.87;p = 0.224),对舒张压(DBP)也无显著降低作用(WMD,-0.53;95%CI,-1.77至0.71;p = 0.401)。此外,四项临床试验的汇总分析表明,食用黑加仑对SBP无降低作用(WMD,-1.46;95%CI,-6.62至3.7;p = 0.579),对DBP也无降低作用(WMD,-2.09;95%CI,-4.38至0.20;p = 0.07)。食用树莓和黑加仑对血压无显著降低作用。需要更精确的随机对照试验来阐明摄入树莓和黑加仑对血压的影响。