Department of Ophthalmology, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, 390-8621, Nagano, Japan.
Jpn J Ophthalmol. 2023 May;67(3):255-263. doi: 10.1007/s10384-023-00980-1. Epub 2023 Feb 16.
To investigate the impact of the local alert levels regarding coronavirus disease 2019 (COVID-19) on the clinical patterns of rhegmatogenous retinal detachment (RRD) in Japan.
Retrospective, single-center, consecutive case series.
We compared two groups of RRD patients, a COVID-19 pandemic group and a control group. Based on the local alert levels in Nagano, five periods during the COVID-19 pandemic were further analyzed: epidemic 1 (state of emergency), inter-epidemic 1, epidemic 2 (second epidemic duration), inter-epidemic 2, and epidemic 3 (third epidemic duration). Patients' characteristics, including symptoms' duration before visiting our hospital, macula status, and retinal detachment (RD) recurrence rate in each period, were compared with those in a control group.
There were 78 patients in the pandemic group and 208 in the control group. The pandemic group had a longer duration of symptoms than the control group (12.0 ± 13.5 days vs. 8.9 ± 14.7 days, P = 0.0045). During the epidemic 1 period, patients had a higher rate of macula-off RRD (71.4% vs. 48.6%) and RD recurrence (28.6% vs. 4.8%) than the control group. This period also demonstrated the highest rates compared to all other periods in the pandemic group.
During the COVID-19 pandemic, RRD patients significantly delayed visiting a surgical facility. They showed a higher rate of macula-off and recurrence compared to the control group during the state of emergency than during other periods of the COVID-19 pandemic, although the difference was not statistically significant due to the small sample size.
调查 2019 年冠状病毒病（COVID-19）本地警戒级别对日本孔源性视网膜脱离（RRD）临床模式的影响。
回顾性、单中心、连续病例系列。
我们比较了两组 RRD 患者，一组是 COVID-19 大流行组，一组是对照组。根据长野的本地警戒级别，我们进一步分析了 COVID-19 大流行期间的五个时期：流行 1（紧急状态）、流行 1 间期、流行 2（第二次流行持续时间）、流行 2 间期和流行 3（第三次流行持续时间）。比较了每个时期患者的特征，包括就诊前症状持续时间、黄斑状态和视网膜脱离（RD）复发率，与对照组进行比较。
大流行组有 78 例患者，对照组有 208 例患者。大流行组的症状持续时间长于对照组（12.0±13.5 天比 8.9±14.7 天，P=0.0045）。在流行 1 期间，与对照组相比，患者中黄斑脱离性 RRD（71.4%比 48.6%）和 RD 复发（28.6%比 4.8%）的发生率更高。与大流行期间的所有其他时期相比，该时期的发生率也最高。
在 COVID-19 大流行期间，RRD 患者明显延迟了前往手术机构就诊。与 COVID-19 大流行期间的其他时期相比，他们在紧急状态下的黄斑脱离和复发率高于对照组，尽管由于样本量小，差异无统计学意义。
