University of Würzburg, Comprehensive Cancer Center Mainfranken, Würzburg, Germany.
Integr Cancer Ther. 2023 Jan-Dec;22:15347354231153172. doi: 10.1177/15347354231153172.
Cancer patients often suffer from psychological symptoms and need psychological support. Especially during the COVID-19 pandemic, eHealth interventions might be helpful to overcome the obstacles of the pandemic. This study evaluates the effectiveness of a video sequence-based eHealth intervention on anxiety, fatigue, and depression in cancer patients.
Patients (N = 157) with different tumor entities were randomly assigned to the video intervention group (IG) and the waiting control group (CG). Patients in the IG received a video intervention comprising 8 video sequences over 4 weeks. The videos included psychoeducation on distress and psychological symptoms, Acceptance and Commitment Therapy elements, and Yoga and Qigong exercises. Patients' anxiety and fear of progression (primary outcomes) and secondary outcomes were assessed before randomization (T1) and after the end of the intervention for IG or the waiting period for CG (T2) using self-reported questionnaires (GAD-7, PA-F-KF, EORTC QLQ-FA12, PHQ-8).
Patients of the IG showed no significant improvement in anxiety (GAD-7; = .75), fear of progression (FoP-Q-SF; = .29), fatigue (EORTC QLQ-FA12; = .72), and depression (PHQ-8; = .95) compared to patients in the waiting CG. However, symptoms of anxiety, fatigue, and depression decreased in both groups. Exploratory subgroup analysis regarding sex, therapy status, therapy goal, and tumor entity showed no effects. Overall, the intervention had a high level of acceptance.
The video intervention was ineffective in reducing the psychological burden compared to a waiting CG. The findings support prior observations of the value of therapeutic guidance and promoting self-management for improving patients' psychological burdens. Further studies are required to evaluate the effectiveness of psycho-oncological eHealth delivered through video sequences.
癌症患者常伴有心理症状，需要心理支持。尤其是在 COVID-19 大流行期间，电子健康干预可能有助于克服大流行带来的障碍。本研究评估了基于视频序列的电子健康干预对癌症患者焦虑、疲劳和抑郁的效果。
患有不同肿瘤实体的患者（N=157）被随机分配到视频干预组（IG）和等待对照组（CG）。IG 组患者接受了包括 8 个视频序列的视频干预，为期 4 周。视频包括有关痛苦和心理症状的心理教育、接受与承诺疗法元素以及瑜伽和气功练习。患者在随机分组前（T1）和 IG 干预结束或 CG 等待期结束后（T2）使用自我报告问卷（GAD-7、PA-F-KF、EORTC QLQ-FA12、PHQ-8）评估焦虑和对进展的恐惧（主要结局）和次要结局。
与等待 CG 相比，IG 组患者的焦虑（GAD-7；=0.75）、对进展的恐惧（FoP-Q-SF；=0.29）、疲劳（EORTC QLQ-FA12；=0.72）和抑郁（PHQ-8；=0.95）无显著改善。然而，两组患者的焦虑、疲劳和抑郁症状均有所减轻。关于性别、治疗状态、治疗目标和肿瘤实体的探索性亚组分析未显示出效果。总体而言，该干预措施的接受程度较高。
与等待 CG 相比，视频干预在减轻心理负担方面效果不佳。这些发现支持了之前关于治疗指导和促进自我管理对于改善患者心理负担的价值的观察结果。需要进一步研究来评估通过视频序列提供的心理肿瘤电子健康的有效性。
