Migaki G, Casey H W, Bayles W B
Registry of Comparative Pathology, Armed Forces Institute of Pathology, Washington, DC 20306-6000.
J Am Vet Med Assoc. 1987 Oct 15;191(8):997-8.
Cerebral phaeohyphomycosis was diagnosed in a 9-year-old spayed dog that had a series of epileptic convulsions a day before death. About 6 weeks before her death, she had been treated for severe demodectic mange. During this period, persistent leukopenia, lymphocytopenia, and thrombocytopenia were found by blood analyses. At necropsy, multiple large pyogranulomatous lesions were found in the cerebrum and meninges. Dematiaceous fungi with brown, branching, septate hyphae and budding yeasts were found within tissue cells and in the necrotic areas.
一只9岁已绝育的犬被诊断为脑暗色丝孢霉病,该犬在死亡前一天出现了一系列癫痫发作。在其死亡前约6周,它曾因严重的蠕形螨病接受治疗。在此期间,血液分析发现持续的白细胞减少、淋巴细胞减少和血小板减少。尸检时,在大脑和脑膜中发现了多个大的脓性肉芽肿性病变。在组织细胞内和坏死区域发现了具有棕色、分支、分隔菌丝和芽生酵母的暗色真菌。