Gómez Santos Elisabet, López Lorente Francisco José, Fernández Fructuoso José Ramón, Cortés Mora Pedro, Fuentes Gutiérrez Carmen, Bosch Giménez Vicente
Hospital Juan Ramón Jiménez, Huelva, Spain.
Hospital Juan Ramón Jiménez, Huelva, Spain.
An Pediatr (Engl Ed). 2023 Mar;98(3):185-193. doi: 10.1016/j.anpede.2023.01.008. Epub 2023 Feb 17.
The fat mass (FM) is greater in late preterm than full term infants at 1 month post birth, which may be an additional risk factor for metabolic syndrome in adulthood.
To evaluate body composition (BC) in late preterm infants using bioelectrical impedance analysis (BIA) to determine which anthropometric parameters are associated with BC. Our hypothesis was that weight-for-length is associated with the length-normalized fat mass index (FMI) at 1 year of life.
We carried out a prospective cohort study in 2 groups: late preterm infants and full term infants. We obtained BC data by BIA. We calculated the fat mass (FM), FMI, fat-free mass (FFM) and length-normalized fat-free mass index (FFMI) at 1, 6 and 12 months of life. After, we assessed the association of the FMI with anthropometric parameters using multiple linear regression analysis.
The study included 97 late preterm and 47 full term infants, although at 12 months of life, the BC assessment was performed on 66 and 33 infants, respectively. Late preterm infants, compared to full term infants, had a higher FFM at 1 month (4013 vs 3524 g), a higher weight velocity at 6 months (5480 g versus 4604 g) and a lower FFM (7232 vs 7813 g) and FFMI (12.55 vs 13.26) at 12 months of life. The multivariate regression analysis showed that the weight-for-length z-core at 12 months was positively associated with the FMI at 12 months in all infants.
The weight-for-length z-score at 12 months is strongly associated with the FMI at 1 year of life. Further studies are needed to investigate whether an increment in this anthropometric parameter may modulate the risk of chronic diseases.
晚期早产儿出生1个月时的脂肪量（FM）高于足月儿，这可能是成年后患代谢综合征的一个额外风险因素。
使用生物电阻抗分析（BIA）评估晚期早产儿的身体成分（BC），以确定哪些人体测量参数与BC相关。我们的假设是，身长别体重与1岁时的身长标准化脂肪量指数（FMI）相关。
我们对两组进行了前瞻性队列研究：晚期早产儿和足月儿。我们通过BIA获得BC数据。我们计算了1、6和12个月龄时的脂肪量（FM）、FMI、去脂体重（FFM）和身长标准化去脂体重指数（FFMI）。之后，我们使用多元线性回归分析评估FMI与人体测量参数之间的关联。
该研究纳入了97名晚期早产儿和47名足月儿，不过在12个月龄时，分别对66名和33名婴儿进行了BC评估。与足月儿相比，晚期早产儿在1个月时的FFM更高（4013克对3524克），在6个月时的体重增长速度更高（5480克对4604克），在12个月龄时的FFM更低（7232克对7813克），FFMI更低（12.55对13.26）。多变量回归分析显示，所有婴儿在12个月时的身长别体重z评分与12个月时的FMI呈正相关。
12个月时的身长别体重z评分与1岁时的FMI密切相关。需要进一步研究来调查该人体测量参数的增加是否可能调节慢性病风险。
