Perng Wei, Conway Rebecca, Mayer-Davis Elizabeth, Dabelea Dana
1Lifecourse Epidemiology of Adiposity and Diabetes (LEAD) Center, University of Colorado Anschutz Medical Campus, Aurora, CO.
2Department of Epidemiology, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO.
Diabetes Care. 2023 Mar 1;46(3):490-499. doi: 10.2337/dci22-0046.
In this narrative review, we describe the epidemiology (prevalence, incidence, temporal trends, and projections) of type 2 diabetes among children and adolescents (<20 years), focusing on data from the U.S. and reporting global estimates where available. Secondarily, we discuss the clinical course of youth-onset type 2 diabetes, from prediabetes to complications and comorbidities, drawing comparisons with youth type 1 diabetes to highlight the aggressive course of this condition, which, only recently, has become recognized as a pediatric disease by health care providers. Finally, we end with an overview of emerging topics in type 2 diabetes research that have potential to inform strategies for effective preventive action at the community and individual levels.
在这篇叙述性综述中，我们描述了儿童和青少年（<20岁）2型糖尿病的流行病学（患病率、发病率、时间趋势和预测），重点关注来自美国的数据，并在可获取的情况下报告全球估计数。其次，我们讨论了青少年发病的2型糖尿病的临床病程，从糖尿病前期到并发症和合并症，并与青少年1型糖尿病进行比较，以突出这种疾病的进展迅猛，而这种疾病直到最近才被医疗保健提供者认可为一种儿科疾病。最后，我们概述了2型糖尿病研究中的新兴主题，这些主题有可能为社区和个人层面的有效预防行动策略提供信息。
