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诺雷科帕:一个用于改进动物研究与试验的全球资源知识库。

Norecopa: A global knowledge base of resources for improving animal research and testing.

作者信息

Smith Adrian J

机构信息

Norecopa, c/o Norwegian Veterinary Institute, Ås, Norway.

出版信息

Front Vet Sci. 2023 Feb 2;10:1119923. doi: 10.3389/fvets.2023.1119923. eCollection 2023.

Abstract

There are good ethical, legal and scientific reasons for ensuring that our use of animals in research and testing is limited to the lowest number of animals, and that those which are used are treated as humanely as possible, while at the same time providing reliable, reproducible and translatable data which is adequately reported. Unfortunately, there is widespread evidence that there is room for improvement in all these areas. This paper describes the Norecopa website, which offers links to global resources which can be used to resolve these issues. Much of the website content is linked to the PREPARE guidelines for planning any research or testing which appears to need animals. Attention to detail on all steps of the pathway from early planning to manuscript submission should lead to better science, improved animal welfare, and fewer health and safety accidents. This will also minimize the chances of manuscript rejection due to inadequate planning, avoiding a waste of human resources and animal lives.

摘要

出于良好的伦理、法律和科学原因,我们应确保在研究和测试中对动物的使用仅限于最少数量的动物,并且对所用动物给予尽可能人道的对待,同时提供可靠、可重复且可转化的数据,并进行充分报告。不幸的是,有广泛的证据表明,在所有这些领域都有改进的空间。本文介绍了Norecopa网站,该网站提供了可用于解决这些问题的全球资源链接。网站的大部分内容都与PREPARE指南相关,该指南用于规划任何似乎需要动物的研究或测试。在从早期规划到稿件提交的整个过程中注重细节,将有助于产生更好的科学成果、改善动物福利,并减少健康和安全事故。这也将最大限度地减少因规划不足而导致稿件被拒的可能性,避免浪费人力资源和动物生命。

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