Aslanger Emre K
Department of Cardiology, Pendik Training and Research Hospital, Marmara University, Istanbul, Turkey.
Turk J Emerg Med. 2022 Sep 28;23(1):1-4. doi: 10.4103/2452-2473.357333. eCollection 2023 Jan-Mar.
The ST-segment elevation (STE) myocardial infarction (MI)/non-STEMI (NSTEMI) paradigm has been the central dogma of emergency cardiology for the last 30 years. Although it was a major breakthrough when it was first introduced, it is now one of the most important obstacles to the further progression of modern MI care. In this article, we trace why a disease with an established underlying pathology (acute coronary occlusion [ACO]) was unintentionally labeled with a surrogate electrocardiographic sign (STEMI/NSTEMI) instead of pathologic substrate itself (ACO-MI/non-ACO-MI or occlusion MI [OMI]/non-OMI [NOMI] for short), how this fundamental mistake caused important clinical consequences, and why we should change this paradigm with a better one, namely OMI/NOMI paradigm.
在过去30年里,ST段抬高型(STE)心肌梗死(MI)/非ST段抬高型心肌梗死(NSTEMI)模式一直是急诊心脏病学的核心教条。尽管它在首次引入时是一项重大突破,但如今却成为现代心肌梗死治疗进一步发展的最重要障碍之一。在本文中,我们追溯了为何一种具有既定潜在病理(急性冠状动脉闭塞[ACO])的疾病被无意中用替代心电图征象(STEMI/NSTEMI)而非病理底物本身(ACO-MI/非ACO-MI或简称为闭塞性心肌梗死[OMI]/非闭塞性心肌梗死[NOMI])来标记,这种根本性错误是如何导致重要临床后果的,以及为何我们应该用更好的模式,即OMI/NOMI模式来改变这一模式。