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首剂新型冠状病毒灭活疫苗(BBIBP-CorV)接种后发生吉兰-巴雷综合征

Guillain-Barré Syndrome Following the First Dose of Inactivated SARS-CoV-2 Vaccine, BBIBP-CorV.

作者信息

Wijekoon Lanka, Sarathchandra Chamara, Siribaddana Sisira

机构信息

Department of Medicine, Rajarata University of Sri Lanka, Anuradhapura, LKA.

出版信息

Cureus. 2023 Jan 18;15(1):e33952. doi: 10.7759/cureus.33952. eCollection 2023 Jan.

Abstract

We present a case report of Guillain-Barré syndrome (GBS) following inactivated whole virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine, BBIBP-CorV. A man presented with paresthesia in both upper and lower limbs with bifacial weakness, onset 18 days after receiving the first BBIBP-CorV vaccine. A bifacial palsy with a paresthesia variant of GBS was diagnosed, and the patient was treated with intravenous immunoglobulin, arresting the progression of neurological symptoms. Clinicians need to be aware of the possibility of GBS following vaccination with BBIBP-CorV, an inactivated SARS-CoV-2 vaccine.

摘要

我们报告了1例接种新型冠状病毒2(SARS-CoV-2)灭活全病毒疫苗BBIBP-CorV后发生吉兰-巴雷综合征(GBS)的病例。一名男性在接种第一剂BBIBP-CorV疫苗18天后出现双上肢和双下肢感觉异常伴双侧面神经麻痹。诊断为伴有感觉异常型GBS的双侧面神经麻痹,患者接受了静脉注射免疫球蛋白治疗,神经症状进展得以控制。临床医生需要意识到接种灭活SARS-CoV-2疫苗BBIBP-CorV后发生GBS的可能性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d1d/9937680/d57b4d06e98b/cureus-0015-00000033952-i01.jpg

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