Institute of Dentistry, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Clin Exp Dent Res. 2023 Apr;9(2):375-387. doi: 10.1002/cre2.716. Epub 2023 Feb 23.
The objective of this review is to assess the available literature systematically related to the effect of silver diamine fluoride (SDF) for the management of occlusal and root carious lesions in permanent teeth regardless of age. MATERIALS AND METHODS: This systematic review was conducted according to the Cochrane Handbook for Systematic Reviews of Interventions and Preferred Reporting Items for Systematic Review and Meta-Analyses statement. A literature search was performed using PubMed/MEDLINE, Cochrane Central Register of Controlled Trials, Web of Science, DOAJ, and Open Gray with no language restrictions up to December 2022. Three reviewers critically assessed the studies for eligibility. Any disputes between the reviewers were handled by a fourth independent reviewer. The quality assessment and data extraction of the studies were performed.
A total of 2176 studies were screened. The titles and abstracts of the studies were then reviewed (n = 346), and 52 studies met the search criteria. Following the full-text review, 11 studies investigated the effect of SDF against other treatments such as chlorhexidine, sodium fluoride, ammonium bifluoride, tricalcium silicate paste, casein phosphopeptide amorphous calcium phosphate, glass ionomer cement (GIC) combined with fluoride varnish, resin-modified GIC, and atraumatic restorative treatment were assessed.
Within the limitations of this review, the use of SDF is promising with high preventative fractions in permanent teeth of children and older populations when compared to other topical applications such as dental varnish containing sodium fluoride.
本综述的目的是评估与银胺氟化物（SDF）用于管理恒牙的窝沟和根面龋病相关的现有文献，无论年龄大小。
本系统综述按照 Cochrane 干预措施系统评价手册和系统评价和荟萃分析报告的首选报告项目进行。检索了 PubMed/MEDLINE、Cochrane 对照试验中心注册库、Web of Science、DOAJ 和 Open Gray 数据库，检索时间截至 2022 年 12 月，无语言限制。三位评审员对研究的合格性进行了严格评估。评审员之间的任何争议都由第四位独立评审员处理。对研究进行了质量评估和数据提取。
共筛选出 2176 项研究。然后对这些研究的标题和摘要进行了审查（n=346），其中 52 项研究符合检索标准。在全文审查后，有 11 项研究评估了 SDF 与其他治疗方法（如洗必泰、氟化钠、单氟磷酸铵、硅酸三钙糊剂、酪蛋白磷酸肽无定形磷酸钙、玻璃离子水门汀（GIC）联合氟化物涂料、树脂改性 GIC 和微创修复治疗）的效果。
在本综述的限制范围内，与含氟牙涂料等其他局部应用相比，SDF 在儿童和老年人群的恒牙中具有较高的预防分数，使用 SDF 是有前景的。
