Centre for Microsystems Technology, Ghent University-IMEC, Ghent, 9052, Belgium.
Max Planck Institute for Polymer Research, 55128, Mainz, Germany.
Adv Mater. 2023 Aug;35(32):e2210035. doi: 10.1002/adma.202210035. Epub 2023 Jun 29.
Memristive technologies promise to have a large impact on modern electronics, particularly in the areas of reconfigurable computing and artificial intelligence (AI) hardware. Meanwhile, the evolution of memristive materials alongside the technological progress is opening application perspectives also in the biomedical field, particularly for implantable and lab-on-a-chip devices where advanced sensing technologies generate a large amount of data. Memristive devices are emerging as bioelectronic links merging biosensing with computation, acting as physical processors of analog signals or in the framework of advanced digital computing architectures. Recent developments in the processing of electrical neural signals, as well as on transduction and processing of chemical biomarkers of neural and endocrine functions, are reviewed. It is concluded with a critical perspective on the future applicability of memristive devices as pivotal building blocks in bio-AI fusion concepts and bionic schemes.
忆阻器技术有望对现代电子学产生重大影响,特别是在可重构计算和人工智能 (AI) 硬件领域。与此同时,忆阻器材料的发展以及技术的进步也为生物医学领域开辟了应用前景,特别是在植入式和片上实验室设备中,先进的传感技术会产生大量数据。忆阻器设备作为生物电子学的连接,将生物传感与计算融合在一起,作为模拟信号的物理处理器,或者在先进的数字计算架构中发挥作用。本文回顾了在处理电神经信号以及神经和内分泌功能的化学生物标志物的转导和处理方面的最新进展。最后,本文从批判性的角度探讨了忆阻器作为生物人工智能融合概念和仿生方案关键构建模块的未来适用性。