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母猪代谢紊乱导致的胎盘功能障碍、胎儿存活与发育:母体氧化应激的影响

Placental Malfunction, Fetal Survival and Development Caused by Sow Metabolic Disorder: The Impact of Maternal Oxidative Stress.

作者信息

Yang Xizi, Hu Ruizhi, Shi Mingkun, Wang Long, Yan Jiahao, Gong Jiatai, Zhang Qianjin, He Jianhua, Wu Shusong

机构信息

Hunan Collaborative Innovation Center for Utilization of Botanical Functional Ingredients, College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China.

出版信息

Antioxidants (Basel). 2023 Feb 2;12(2):360. doi: 10.3390/antiox12020360.

DOI:10.3390/antiox12020360
PMID:36829919
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9951909/
Abstract

The energy and metabolic state of sows will alter considerably over different phases of gestation. Maternal metabolism increases dramatically, particularly in late pregnancy. This is accompanied by the development of an increase in oxidative stress, which has a considerable negative effect on the maternal and the placenta. As the only link between the maternal and the fetus, the placenta is critical for the maternal to deliver nutrients to the fetus and for the fetus' survival and development. This review aimed to clarify the changes in energy and metabolism in sows during different pregnancy periods, as well as the impact of maternal oxidative stress on the placenta, which affects the fetus' survival and development.

摘要

母猪的能量和代谢状态在妊娠的不同阶段会发生显著变化。母体代谢大幅增加,尤其是在妊娠后期。与此同时,氧化应激加剧,这对母体和胎盘产生了相当大的负面影响。作为母体与胎儿之间的唯一联系,胎盘对于母体向胎儿输送营养物质以及胎儿的生存和发育至关重要。本综述旨在阐明母猪在不同孕期的能量和代谢变化,以及母体氧化应激对胎盘的影响,而胎盘会影响胎儿的生存和发育。

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