Moscatelli Sara, Bianco Francesco, Cimini Andrea, Panebianco Mario, Leo Isabella, Bucciarelli-Ducci Chiara, Perrone Marco Alfonso
Paediatric Cardiology Department, Royal Brompton and Harefield Hospitals, Guy's and St Thomas' NHS Foundation Trust, London SW3 5NP, UK.
Cardiovascular Sciences Department, AOU "Ospedali Riuniti", 60126 Ancona, Italy.
Children (Basel). 2023 Jan 26;10(2):218. doi: 10.3390/children10020218.
Although not frequent in the pediatric population, ischemia could occur in children due to several congenital and acquired disease. Stress imaging is key for the non-invasive evaluation of myocardial abnormalities and perfusion defect in this clinical setting. Moreover, beyond ischemia assessment, it can provide complementary diagnostic and prognostic information in valvular heart disease and cardiomyopathies. When performed using cardiovascular magnetic resonance, it could detect, in addition, myocardial fibrosis and infarction, increasing the diagnostic yield. Several imaging modalities are currently available for the evaluation of stress myocardial perfusion. Advances in technologies have also increased the feasibility, safety and availability of these modalities in the pediatric age group. However, despite the established role of stress imaging and its increasing use in daily clinical practice, there are currently no specific guidelines, and little data are available in the literature on this topic. The aim of this review is to summarize the most recent evidence on pediatric stress imaging and its clinical application with a focus on the advantages and limitations of each imaging modality currently available.
虽然在儿科人群中并不常见，但由于多种先天性和后天性疾病，儿童也可能发生缺血。在这种临床情况下，负荷成像对于无创评估心肌异常和灌注缺损至关重要。此外，除了缺血评估外，它还可以在瓣膜性心脏病和心肌病中提供补充性的诊断和预后信息。当使用心血管磁共振进行负荷成像时，还可以检测到心肌纤维化和梗死，提高诊断率。目前有几种成像方式可用于评估负荷心肌灌注。技术的进步也提高了这些方式在儿科年龄组中的可行性、安全性和可及性。然而，尽管负荷成像已确立其作用且在日常临床实践中的应用越来越多，但目前尚无具体指南，关于该主题的文献数据也很少。本综述的目的是总结儿科负荷成像的最新证据及其临床应用，重点关注目前可用的每种成像方式的优缺点。
