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林恩:重要植物化学和药理化合物的天然储存库。

Linn.: A Natural Repository of Vital Phytochemical and Pharmacological Compounds.

作者信息

Bhat Aeyaz Ahmad, Shakeel Adnan, Rafiq Sadaf, Farooq Iqra, Malik Azad Quyoom, Alghuthami Mohammed E, Alharthi Sarah, Qanash Husam, Alharthy Saif A

机构信息

Department of Chemistry, Lovely Professional University, Phagwara 144411, India.

Department of Botany, Aligarh Muslim University, Aligarh 202002, India.

出版信息

Life (Basel). 2023 Jan 30;13(2):380. doi: 10.3390/life13020380.

DOI:10.3390/life13020380
PMID:36836737
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9962597/
Abstract

Linn. is a valuable medicinal plant that possesses the therapeutic potential to treat a wide range of diseases in humans. It has been known to have significant nutritional and curative properties since ancient times, and almost all parts of this plant have been utilized to cure numerous fungal and bacterial disorders. The separation and identification of the active ingredients in as well as the testing of those active compounds for pharmacological properties are currently of great interest. Recently, the naphthoquinones extracted from walnut have been observed to inhibit the enzymes essential for viral protein synthesis in the SARS-CoV-2. Anticancer characteristics have been observed in the synthetic triazole analogue derivatives of juglone, and the unique modifications in the parent derivative of juglone have paved the way for further synthetic research in this area. Though there are some research articles available on the pharmacological importance of , a comprehensive review article to summarize these findings is still required. The current review, therefore, abridges the most recent scientific findings about antimicrobial, antioxidant, anti-fungal, and anticancer properties of various discovered and separated chemical compounds from different solvents and different parts of .

摘要

林奈。是一种有价值的药用植物,具有治疗人类多种疾病的治疗潜力。自古以来,人们就知道它具有显著的营养和治疗特性,这种植物的几乎所有部分都被用于治疗多种真菌和细菌疾病。目前,人们对该植物中活性成分的分离和鉴定以及这些活性化合物的药理特性测试非常感兴趣。最近,从核桃中提取的萘醌已被观察到能抑制严重急性呼吸综合征冠状病毒2(SARS-CoV-2)中病毒蛋白合成所必需的酶。胡桃醌的合成三唑类似物衍生物已被观察到具有抗癌特性,胡桃醌母体衍生物的独特修饰为该领域的进一步合成研究铺平了道路。尽管有一些关于该植物药理重要性的研究文章,但仍需要一篇全面的综述文章来总结这些发现。因此,本综述总结了从该植物不同溶剂和不同部位发现和分离出的各种化合物的抗菌、抗氧化、抗真菌和抗癌特性的最新科学发现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/35c2/9962597/9854ddee1704/life-13-00380-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/35c2/9962597/e6537f3e8f8a/life-13-00380-g001.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/35c2/9962597/4dc4ba7179c5/life-13-00380-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/35c2/9962597/f092aff33582/life-13-00380-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/35c2/9962597/ce545e686636/life-13-00380-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/35c2/9962597/826abbe120ae/life-13-00380-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/35c2/9962597/9854ddee1704/life-13-00380-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/35c2/9962597/e6537f3e8f8a/life-13-00380-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/35c2/9962597/a69b4ef970af/life-13-00380-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/35c2/9962597/4dc4ba7179c5/life-13-00380-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/35c2/9962597/f092aff33582/life-13-00380-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/35c2/9962597/ce545e686636/life-13-00380-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/35c2/9962597/826abbe120ae/life-13-00380-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/35c2/9962597/9854ddee1704/life-13-00380-g007.jpg

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