López-Muñoz Alfredo, Gargallo-Martínez Beatriz, Sánchez-González María Carmen, Capote-Puente Raúl, De-Hita-Cantalejo Concepción, Romero-Luna Marta, Conejero-Domínguez Juan-José, Sánchez-González José-María
Department of Physics of Condensed Matter, Optics Area, Vision Sciences Research Group (CIVIUS), Pharmacy School, University of Seville, 41009 Seville, Spain.
Research & Development Department (Miranza Virgen de Luján®), Ophthalmology Center, 41011 Seville, Spain.
Life (Basel). 2023 Feb 4;13(2):447. doi: 10.3390/life13020447.
The aim of this study was to evaluate the relationship between myopia and ocular biometric variables using the Pentacam AXL single rotation Scheimpflug camera. This prospective, cross-sectional, single-center study was performed in fifty Caucasian patients aged between 18 and 30 years (24.84 ± 3.04 years). The measured variables included maximum and minimum keratometry (K1 and K2, respectively), anterior chamber depth (ACD), corneal horizontal diameter or white to white (WTW), central corneal thickness (CCT), corneal asphericity (Q), and axial length (AXL). The tomographic and biometric measurements were considered optimal when the quality factor was greater than 95% according to the manufacturer's software instructions. The AXL presented a significant correlation with the spherical equivalent without cycloplegia (SE without CP), age at onset of myopia (r = -0.365, = 0.012), mean keratometry (Km) (r = -0.339, = 0.016), ACD (r = 0.304, = 0.032), and WTW (r = 0.406, = 0.005). The eyes with AXL higher than 25 mm had earlier onset; higher SE without CP, AXL, and Q; and a flatter Km. AXL is the biometric variable with the greatest influence on the final refractive state in the adult myopic eye. Ophthalmologists and optometric management must consider these biometric differences in order to identify the most appropriate correction techniques in each case. The use of the Pentacam AXL in ocular biometric measurement is effective, reproducible, and non-invasive.
本研究旨在使用Pentacam AXL单旋转Scheimpflug相机评估近视与眼部生物测量变量之间的关系。这项前瞻性、横断面、单中心研究在50名年龄在18至30岁（平均24.84±3.04岁）的白种人患者中进行。测量的变量包括最大和最小角膜曲率（分别为K1和K2）、前房深度（ACD）、角膜水平直径或白对白（WTW）、中央角膜厚度（CCT）、角膜非球面性（Q）和眼轴长度（AXL）。根据制造商的软件说明，当质量因子大于95%时，断层扫描和生物测量被认为是最佳的。AXL与未散瞳的等效球镜度（SE without CP）、近视发病年龄（r = -0.365，P = 0.012）、平均角膜曲率（Km）（r = -0.339，P = 0.016）、ACD（r = 0.304，P = 0.032）和WTW（r = 0.406，P = 0.005）呈显著相关。AXL高于25mm的眼睛发病较早；SE without CP、AXL和Q较高；Km较平坦。AXL是对成人近视眼最终屈光状态影响最大的生物测量变量。眼科医生和验光管理必须考虑这些生物测量差异，以便在每种情况下确定最合适的矫正技术。Pentacam AXL在眼部生物测量中的应用是有效、可重复且无创的。
