Richardson Elise A, Roe R Michael, Apperson Charles S, Ponnusamy Loganathan
Department of Entomology and Plant Pathology, North Carolina State University, Raleigh, NC 27695, USA.
Microorganisms. 2023 Feb 16;11(2):493. doi: 10.3390/microorganisms11020493.
is a potentially pathogenic species of within the spotted fever group vectored by ticks. While many studies have been published on this species, there is debate over its pathogenicity and the inhibitory role it plays in diagnosing illnesses caused by other spotted fever group species. Many publications have recorded the high infection prevalence of in tick populations at a global scale. While this species is rather ubiquitous, questions remain over the epidemiological importance of this possible human pathogen. With tick-borne diseases on the rise, understanding the exact role that plays as a pathogen and inhibitor of infection relative to other tick-borne pathogens will help public health efforts. The goal of this review was to compile the known literature on , review what we know about its geographic distribution, tick vectors, and pathogenicity, assess relatedness between various international strains from ticks by phylogenetic analysis and draw conclusions regarding future research needed.
是斑点热群中一种由蜱传播的潜在致病物种。虽然已经发表了许多关于该物种的研究,但关于其致病性以及它在诊断由其他斑点热群物种引起的疾病中所起的抑制作用仍存在争议。许多出版物记录了该物种在全球蜱种群中的高感染率。虽然该物种相当普遍,但关于这种可能的人类病原体的流行病学重要性仍存在疑问。随着蜱传疾病的增加,了解该物种相对于其他蜱传病原体作为病原体和感染抑制剂的确切作用将有助于公共卫生工作。本综述的目的是汇编关于该物种的已知文献,回顾我们对其地理分布、蜱传播媒介和致病性的了解,通过系统发育分析评估来自蜱的各种国际菌株之间的相关性,并就未来所需的研究得出结论。