一项针对年轻男性的自我引导式生活方式干预：ACTIVATE随机试点试验的结果

A Self-Guided Lifestyle Intervention for Young Men: Findings from the ACTIVATE Randomized Pilot Trial.

作者信息

Reading Jean M, Crane Melissa M, Carlyle Kellie, Perera Robert A, LaRose Jessica Gokee

机构信息

Department of Health Behavior and Policy, Virginia Commonwealth University School of Medicine, Richmond, VA 23219, USA.

Department of Preventive Medicine, Rush University Medical Center, Chicago, IL 60612, USA.

出版信息

J Mens Health. 2022;18(9). doi: 10.31083/j.jomh1809191. Epub 2022 Sep 14.

DOI:10.31083/j.jomh1809191

PMID:36846742

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9949796/

Abstract

BACKGROUND

Young men are at high risk for developing obesity-related health complications, yet are markedly underrepresented in lifestyle interventions. This pilot study examined the feasibility and preliminary efficacy of a lifestyle intervention (self-guided + health risk messaging) targeting young men.

METHODS

35 young men (Age = 29.3 ± 4.27; BMI = 30.8 ± 4.26; 34% racial/ethnic minority) were randomly assigned to the intervention or delayed treatment control. The intervention (ACTIVATE) included 1 virtual group session, digital tools (wireless scale, self-monitoring app), access to self-paced content via a secure website, and 12 weekly texts to reinforce health risk messaging. Fasted objective weight was assessed remotely at baseline and 12-weeks. Perceived risk was assessed via survey at baseline, 2-week, and 12-week. -tests were used to compare weight outcomes between arms. Linear regressions examined the association between percent weight change and perceived risk change.

RESULTS

Recruitment was successful as evidenced by 109% of target enrollment achieved in a 2-month period. Retention was 86% at 12 weeks, with no differences by arm ( = 0.17). Participants in the intervention arm experienced modest weight loss at 12 weeks, whereas slight gains were observed in the control arm (-1.6% ± 2.5 +0.31% ± 2.8, = 0.04). Change in perceived risk was not associated with change in percent weight ( > 0.05).

CONCLUSIONS

A self-guided lifestyle intervention showed initial promise for weight management among young men, but these findings are limited by small sample size. More research is needed to bolster weight loss outcomes while retaining the scalable self-guided approach.

CLINICAL TRIAL REGISTRATION

NCT04267263 (https://www.clinicaltrials.gov/ct2/show/NCT04267263).

摘要

背景

年轻男性患肥胖相关健康并发症的风险很高，但在生活方式干预中所占比例明显过低。这项试点研究检验了针对年轻男性的生活方式干预（自我引导+健康风险信息传递）的可行性和初步疗效。

方法

35名年轻男性（年龄=29.3±4.27；体重指数=30.8±4.26；34%为少数族裔）被随机分配到干预组或延迟治疗对照组。干预措施（ACTIVATE）包括1次虚拟小组会议、数字工具（无线秤、自我监测应用程序）、通过安全网站访问自定进度的内容，以及每周发送12条短信以强化健康风险信息。在基线和12周时远程评估空腹客观体重。在基线、2周和12周时通过调查评估感知风险。使用t检验比较两组之间的体重结果。线性回归分析了体重变化百分比与感知风险变化之间的关联。