循环外泌体在脑血管病中的作用：全面综述。
Role of Circulating Exosomes in Cerebrovascular Diseases: A Comprehensive Review.
机构信息
Department of Neurovascular Centre, Changhai Hospital, Naval Medical University, Shanghai, 200433, China.
Department of Nerurosurgery, Naval Medical Center of PLA, Navy Medical University, Shanghai, 200050, China.
出版信息
Curr Neuropharmacol. 2023;21(7):1575-1593. doi: 10.2174/1570159X21666230214112408.
Exosomes are lipid bilayer vesicles that contain multiple macromolecules secreted by the parent cells and play a vital role in intercellular communication. In recent years, the function of exosomes in cerebrovascular diseases (CVDs) has been intensively studied. Herein, we briefly review the current understanding of exosomes in CVDs. We discuss their role in the pathophysiology of the diseases and the value of the exosomes for clinical applications as biomarkers and potential therapies.
外泌体是由亲代细胞分泌的含有多种大分子的脂质双层囊泡，在细胞间通讯中发挥着重要作用。近年来，外泌体在脑血管疾病（CVDs）中的作用受到了广泛的研究。本文简要综述了外泌体在 CVDs 中的研究进展，讨论了其在疾病病理生理学中的作用，以及作为生物标志物和潜在治疗方法的临床应用价值。
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