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经氯处理的艾柯病毒的部分再激活

Partial reactivation of chlorine-treated echovirus.

作者信息

Young D C, Sharp D G

出版信息

Appl Environ Microbiol. 1979 Apr;37(4):766-73. doi: 10.1128/aem.37.4.766-773.1979.

DOI:10.1128/aem.37.4.766-773.1979
PMID:36850
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC243294/
Abstract

After treatment of a dispersed suspension of echovirus with HOCl, much of the lost plaque titer was restored if the treated virus was induced to aggregate by adjustment of the suspending medium to pH 4.5. This did not appear to be a repair of individual virions but rather a special kind of multiplicity-related increase in plaquing efficiency which occurred when the host cell received several of the damaged virions in a clump.

摘要

用次氯酸处理埃可病毒的分散悬浮液后,如果通过将悬浮培养基的pH值调至4.5诱导处理后的病毒聚集,大部分损失的噬斑效价得以恢复。这似乎不是单个病毒粒子的修复,而是一种特殊的与复数感染相关的噬斑形成效率增加,当宿主细胞在一团中接收到几个受损病毒粒子时就会发生这种情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a633/243294/ef0a7fd3651f/aem00208-0113-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a633/243294/e48b6b3a698c/aem00208-0109-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a633/243294/ef0a7fd3651f/aem00208-0113-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a633/243294/e48b6b3a698c/aem00208-0109-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a633/243294/ef0a7fd3651f/aem00208-0113-a.jpg

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本文引用的文献

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Genetics. 1949 Mar;34(2):93-125. doi: 10.1093/genetics/34.2.93.
2
Reactivation of Irradiated Bacteriophage by Transfer of Self-Reproducing Units.通过自我复制单位的转移实现辐照噬菌体的复活
Proc Natl Acad Sci U S A. 1947 Sep;33(9):253-64. doi: 10.1073/pnas.33.9.253.
3
Multiplicity reactivation and marker rescue with vaccinia virus.痘苗病毒的多重复活与标记拯救
水中氯对艾柯病毒的病毒粒子构象形式及复杂失活动力学
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Virology. 1962 Aug;17:511-9. doi: 10.1016/0042-6822(62)90150-2.
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Influence of the physical state of formalinized vaccinia virus particles on surviving plaque titer: evidence for multiplicity reactivation.甲醛化痘苗病毒颗粒的物理状态对存活蚀斑效价的影响:多重复活的证据
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Multiplicity reactivation of vaccinia virus in the cells of the chorioallantoic membrane.痘苗病毒在绒毛尿囊膜细胞中的多重复活
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