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含奥菲癣菌和3%葡萄糖酸氯己定的日常护理垫在患有局部皮肤细菌感染和/或过度生长的犬只中的性能

Performance of Daily Pads Containing Ophytrium and Chlorhexidine Digluconate 3% in Dogs With Local Cutaneous Bacterial and/or Overgrowth.

作者信息

Gatellet Marina, Kesteman Roxane, Baulez Benjamin, Pradiès Félix, Cadot Pierre-Marie, Dropsy Hélène, Fiora Pierre, Mathet Jean-Loup, Ollivier Elodie, Billy Charlotte, Zemirline Claudine, De Jaeger Xavier

机构信息

Ceva Santé Animale, Libourne, France.

Clinique Vétérinaire VPLUS, Saint Aubin de Blaye, France.

出版信息

Front Vet Sci. 2021 May 7;8:579074. doi: 10.3389/fvets.2021.579074. eCollection 2021.

Abstract

Local disturbances of the microbiota are common in dogs with underlying skin conditions. Antiseptic topical products are indicated to control such superficial disorders. The objective of this study was to evaluate the performance of a daily application of pads containing Ophytrium and chlorhexidine digluconate 3% (DOUXO® S3 PYO Pads, Ceva Santé Animale, France) in dogs with focal bacterial and/or overgrowth. Eighteen dogs with focal skin dysbiosis were included in the analysis of this prospective, multicentric, field study. Dogs received daily pad applications for 14 days. Bacterial and/or counts per microscopic field and a global score of the most affected patch (0-17 scale based on extension, severity, bacterial, and cytological scores) were assessed by a veterinarian and pruritus by the owner (Pruritus Visual Analog Scale) on days (D)0, D7, D14. Owner and veterinarian evaluations for performance and satisfaction were recorded. Eleven dogs had primarily cocci overgrowth and seven mostly . Mean bacterial and counts decreased after 14 days (6.9-1.1; 7.6-1.5, respectively); 88.9% of dogs achieved a ≥70% microbial decrease and had ≤2 bacteria and ≤1 per oil field. Mean global score of the most affected patch and pruritus score significantly improved at D14, respectively, from 8.6 to 2.6 and 4.5 to 1.2 ( < 0.05 each, mean improvements of 70.4 and 71.4%, respectively). Global veterinary assessment of the protocol was satisfactory, good, or excellent in 88.9% of cases. Most owners (94.4%) considered the protocol efficacious. Using a pad containing Ophytrium and chlorhexidine digluconate 3% daily for 14 days improved the skin condition and pruritus of dogs with local dysbiosis, resulting in high satisfaction levels for both veterinarians and dog owners.

摘要

微生物群的局部紊乱在患有潜在皮肤疾病的犬中很常见。抗菌外用产品可用于控制此类浅表性疾病。本研究的目的是评估每日使用含有奥菲癣菌和3%葡萄糖酸氯己定的垫(DOUXO® S3 PYO垫,法国诗华动物保健公司)对患有局灶性细菌和/或过度生长的犬的疗效。18只患有局灶性皮肤生态失调的犬被纳入这项前瞻性、多中心、实地研究的分析。犬每日使用垫,持续14天。在第0天、第7天、第14天,由兽医评估每个显微镜视野中的细菌和/或数量以及最受影响斑块的总体评分(基于范围、严重程度、细菌和细胞学评分的0 - 17分制),由主人评估瘙痒程度(瘙痒视觉模拟量表)。记录主人和兽医对疗效和满意度的评价。11只犬主要为球菌过度生长,7只主要为……平均细菌和数量在14天后减少(分别从6.9降至1.1;从7.6降至1.5);88.9%的犬实现了≥70%的微生物减少,且每个视野中细菌≤2个、……≤1个。最受影响斑块的平均总体评分和瘙痒评分在第14天分别从8.6显著改善至2.6以及从4.5显著改善至1.2(均P < 0.

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f481/8138468/6a89c16b4628/fvets-08-579074-g0001.jpg

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