皮肤癌光动力治疗的全球趋势与研究进展：文献计量分析与文献综述

Global Trends and Research Progress of Photodynamic Therapy in Skin Cancer: A Bibliometric Analysis and Literature Review.

作者信息

Sun Jiachen, Zhao Hongqing, Fu Lin, Cui Jing, Yang Yuguang

机构信息

Department of Dermatology, Fourth Medical Center of Chinese PLA General Hospital, Beijing, People's Republic of China.

Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China.

出版信息

Clin Cosmet Investig Dermatol. 2023 Feb 21;16:479-498. doi: 10.2147/CCID.S401206. eCollection 2023.

DOI:10.2147/CCID.S401206

PMID:36851952

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9961166/

Abstract

BACKGROUND

Based on photochemical reactions through the combined use of light and photosensitizers, photodynamic therapy (PDT) is gaining popularity for the treatment of skin cancer. Various photosensitizers and treatment regimens are continuously being developed for enhancing the efficacy of PDT on skin cancer. Reviewing the development history of PDT on skin cancer, and summarizing its development direction and research status, is conducive to the further research.

METHODS

To evaluate the research trends and map knowledge structure, all publications covering PDT on skin cancer were retrieved and extracted from Web of Science database. We applied VOSviewer and CiteSpace softwares to evaluate and visualize the countries, institutes, authors, keywords and research trends. Literature review was performed for the analysis of the research status of PDT on skin cancer.

RESULTS

A total of 2662 publications were identified. The elements, mechanism, pros and cons, representative molecular photosensitizers, current challenges and research progress of PDT on skin cancer were reviewed and summarized.

CONCLUSION

This study provides a comprehensive display of the field of PDT on skin cancer, which will help researchers further explore the mechanism and application of PDT more effectively and intuitively.

摘要