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肺癌治疗中的纳米技术:一篇叙述性综述。

Nanotechnology in Lung Cancer Therapeutics: A Narrative Review.

作者信息

Koutu Vaibhav, Gupta Manish, Das Saikat, Rawat Deepak K, Kharade Vipin, Pasricha Rajesh K

机构信息

Radiotherapy, All India Institute of Medical Sciences, Bhopal, Bhopal, IND.

出版信息

Cureus. 2023 Jan 26;15(1):e34245. doi: 10.7759/cureus.34245. eCollection 2023 Jan.

Abstract

To date, cancer continues to be one of the biggest challenges for medical science. Nanotechnology has enabled us to overcome some of the limitations of conventional treatment in lung cancer therapeutics. Recently, US Food and Drug Administration (FDA) has approved certain nanomedicines for clinical administration against lung cancer. This article presents a narrative review of approved nanomedicines in lung cancer with a special focus on the results of recently concluded and ongoing clinical trials. The limitations associated with using nanomaterials as anti-lung cancer therapeutic agents and the possible mechanisms to overcome these limitations are also discussed.

摘要

迄今为止,癌症仍然是医学科学面临的最大挑战之一。纳米技术使我们能够克服肺癌治疗中传统疗法的一些局限性。最近,美国食品药品监督管理局(FDA)已批准某些纳米药物用于肺癌的临床治疗。本文对已批准的肺癌纳米药物进行了叙述性综述,特别关注了近期结束和正在进行的临床试验结果。还讨论了将纳米材料用作抗肺癌治疗药物的相关局限性以及克服这些局限性的可能机制。

相似文献

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Nanotechnology in Lung Cancer Therapeutics: A Narrative Review.肺癌治疗中的纳米技术:一篇叙述性综述。
Cureus. 2023 Jan 26;15(1):e34245. doi: 10.7759/cureus.34245. eCollection 2023 Jan.
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本文引用的文献

1
Anti-cancer activity of sustained release capsaicin formulations.持续释放辣椒素制剂的抗癌活性。
Pharmacol Ther. 2022 Oct;238:108177. doi: 10.1016/j.pharmthera.2022.108177. Epub 2022 Mar 26.
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Smart Nanotherapeutics and Lung Cancer.智能纳米疗法与肺癌
Pharmaceutics. 2021 Nov 20;13(11):1972. doi: 10.3390/pharmaceutics13111972.
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Current hurdles to the translation of nanomedicines from bench to the clinic.纳米药物从实验室到临床应用的当前障碍。
Drug Deliv Transl Res. 2022 Mar;12(3):500-525. doi: 10.1007/s13346-021-01024-2. Epub 2021 Jul 23.
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Engineering precision nanoparticles for drug delivery.工程化精准纳米颗粒用于药物递送。
Nat Rev Drug Discov. 2021 Feb;20(2):101-124. doi: 10.1038/s41573-020-0090-8. Epub 2020 Dec 4.

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