Koutu Vaibhav, Gupta Manish, Das Saikat, Rawat Deepak K, Kharade Vipin, Pasricha Rajesh K
Radiotherapy, All India Institute of Medical Sciences, Bhopal, Bhopal, IND.
Cureus. 2023 Jan 26;15(1):e34245. doi: 10.7759/cureus.34245. eCollection 2023 Jan.
To date, cancer continues to be one of the biggest challenges for medical science. Nanotechnology has enabled us to overcome some of the limitations of conventional treatment in lung cancer therapeutics. Recently, US Food and Drug Administration (FDA) has approved certain nanomedicines for clinical administration against lung cancer. This article presents a narrative review of approved nanomedicines in lung cancer with a special focus on the results of recently concluded and ongoing clinical trials. The limitations associated with using nanomaterials as anti-lung cancer therapeutic agents and the possible mechanisms to overcome these limitations are also discussed.
迄今为止，癌症仍然是医学科学面临的最大挑战之一。纳米技术使我们能够克服肺癌治疗中传统疗法的一些局限性。最近，美国食品药品监督管理局（FDA）已批准某些纳米药物用于肺癌的临床治疗。本文对已批准的肺癌纳米药物进行了叙述性综述，特别关注了近期结束和正在进行的临床试验结果。还讨论了将纳米材料用作抗肺癌治疗药物的相关局限性以及克服这些局限性的可能机制。
