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生物相容聚合物纳米构建体:癌症治疗诊断的有效平台。

Biocompatible Polymer Nano-Constructs: A Potent Platform for Cancer Theranostics.

机构信息

Department of Chemistry, 28678Indian Institute of Technology Guwahati, Guwahati, India.

Department of Chemistry, Savitribai Phule Pune University, Pune, Maharashtra, India.

出版信息

Technol Cancer Res Treat. 2023 Jan-Dec;22:15330338231160391. doi: 10.1177/15330338231160391.

DOI:10.1177/15330338231160391
PMID:36855787
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9983094/
Abstract

Nano-constructs of biocompatible polymers have drawn wide attention owing to their potential as theranostics for simultaneous therapy and detection of cancer. The present mini review summarizes various nano-architectures of polymers that have been developed as theranostic agents for the simultaneous treatment and diagnosis of cancer in a single platform. Additionally, research prospects of polymeric cancer theranostics for the future have been highlighted.

摘要

生物相容聚合物的纳米结构由于其在癌症的治疗和检测方面的潜在应用而受到广泛关注。本综述总结了各种聚合物纳米结构,它们已被开发为单一平台中用于癌症的联合治疗和诊断的治疗诊断试剂。此外,还强调了聚合物癌症治疗诊断学的未来研究前景。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ad7/9983094/69fea3b7f863/10.1177_15330338231160391-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ad7/9983094/1c8e27c66570/10.1177_15330338231160391-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ad7/9983094/d85a7fd55225/10.1177_15330338231160391-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ad7/9983094/69fea3b7f863/10.1177_15330338231160391-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ad7/9983094/1c8e27c66570/10.1177_15330338231160391-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ad7/9983094/d85a7fd55225/10.1177_15330338231160391-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ad7/9983094/69fea3b7f863/10.1177_15330338231160391-fig3.jpg

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本文引用的文献

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New Magneto-Fluorescent Hybrid Polymer Nanogel for Theranostic Applications.用于诊疗应用的新型磁荧光杂化聚合物纳米凝胶
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Optimally designed theranostic system based folic acids and chitosan as a promising mucoadhesive delivery system for encapsulating curcumin LbL nano-template against invasiveness of breast cancer.
用于癌症治疗的近红外响应型天然高分子水凝胶组装药物的研究进展
Pharmaceutics. 2023 Dec 4;15(12):2729. doi: 10.3390/pharmaceutics15122729.
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Chemically Modified Natural Polymer-Based Theranostic Nanomedicines: Are They the Golden Gate toward a Clinical Approach against Cancer?基于化学修饰天然聚合物的治疗诊断纳米药物:它们是否是通向癌症临床治疗方法的金门?
ACS Biomater Sci Eng. 2020 Jan 13;6(1):134-166. doi: 10.1021/acsbiomaterials.9b00802. Epub 2019 Dec 11.
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