Haşlak Fatih, Guliyeva Vafa, Hotaman Büşra, Duman Çisem, Yıldız Mehmet, Günalp Aybüke, Aslan Esma, Kılıç Könte Elif, Aliyeva Ayten, Adrovic Amra, Şahin Sezgin, Barut Kenan, Kasapçopur Özgür
Department of Pediatric Rheumatology, İstanbul University-Cerrahpaşa, Cerrahpaşa Faculty of Medicine, İstanbul, Turkey.
Turk Arch Pediatr. 2023 Mar;58(2):212-219. doi: 10.5152/TurkArchPediatr.2023.22303.
Juvenile idiopathic arthritis is a heterogeneous group of disorders and is the most common rheumatic condition in childhood. There are scarce data regarding all comorbidities in juvenile idiopathic arthritis patients.
We aimed to identify the non-rheumatic comorbidities in our juvenile idiopathic arthritis patients. Data were obtained cross-sectionally from the medical records and the face-to-face interviews for 6 consecutive months. Those with more than 1 rheumatic disease were excluded, and conditions that were highly related to the disease, such as uveitis, were not taken into account.
The study included 459 patients with female dominance (62.1%, n = 285). The median age of the patients was 12.87 (1.53-20.95) years. One hundred fifty patients (32.7%) had at least 1 comorbidity (5 patients had 3 comorbidities, and 24 patients had 2 comorbidities). The most common 3 non-rheumatic accompanying medical conditions in our patients were allergic rhinitis (n = 37, 8.1%), attention-deficit hyperactivity disorder (n = 35, 7.6%), and atopic dermatitis (n = 28, 6.1%). None of our patients with systemic JIA had any autoimmune disease. All the patients with primary immune deficiencies had anti-nuclear antibody positivity.
Almost one-third of our patients had at least one comorbidity. This finding might be very helpful to us in planning our multi-disciplinary approach to our patients.
幼年特发性关节炎是一组异质性疾病，是儿童期最常见的风湿性疾病。关于幼年特发性关节炎患者所有合并症的数据很少。
我们旨在确定幼年特发性关节炎患者的非风湿性合并症。数据通过连续6个月从病历和面对面访谈中横断面获取。排除患有1种以上风湿性疾病的患者，且不考虑与该疾病高度相关的情况，如葡萄膜炎。
该研究纳入459例患者，女性占优势（62.1%，n = 285）。患者的中位年龄为12.87（1.53 - 20.95）岁。150例患者（32.7%）至少有一种合并症（5例患者有3种合并症，24例患者有2种合并症）。我们患者中最常见的3种非风湿性伴随疾病是变应性鼻炎（n = 37，8.1%）、注意力缺陷多动障碍（n = 35，7.6%）和特应性皮炎（n = 28，6.1%）。我们的全身型幼年特发性关节炎患者均无自身免疫性疾病。所有原发性免疫缺陷患者抗核抗体均呈阳性。
我们几乎三分之一的患者至少有一种合并症。这一发现可能对我们规划针对患者的多学科治疗方法非常有帮助。
